(Q38472322)

3 September 2017

1 reference

title

Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies (English)

1 reference

3 September 2017

main subject

neoplastic stem cells

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Chiara Raggi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Hani S Mousa

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

M Correnti

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

A Sica

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

11 May 2015

1 reference

3 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

671-682

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25961921%20AND%20SRC:MED&resulttype=core&format=json

Biological diversity in metastatic neoplasms: origins and implications.

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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

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STAT3 or USF2 contributes to HIF target gene specificity

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Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal

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Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells

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STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells

21 January 2018

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IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

21 January 2018

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Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

21 January 2018

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beta-Catenin: a pivot between cell adhesion and Wnt signalling

21 January 2018

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Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions

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Notch signaling: cell fate control and signal integration in development

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Mammary stem cells and breast cancer--role of Notch signalling.

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The Notch pathway is important in maintaining the cancer stem cell population in pancreatic cancer

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p21 in cancer: intricate networks and multiple activities

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Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

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Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

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Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation

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Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

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Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

21 January 2018

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Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer

21 January 2018

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Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2

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Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway

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Inflammation, a key event in cancer development

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The role of EGF-related peptides in tumor growth.

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Epidermal growth factor-related peptides and their receptors in human malignancies

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EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling

21 January 2018

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21 January 2018

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Breast cancer stem cells, cytokine networks, and the tumor microenvironment

21 January 2018

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Impact of microenvironment and stem-like plasticity in cholangiocarcinoma: molecular networks and biological concepts.

21 January 2018

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Stem cells and their niches

21 January 2018

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Tumor-associated macrophages in SHH subgroup of medulloblastomas

21 January 2018

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Tumor-associated macrophages: from mechanisms to therapy

21 January 2018

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The yin-yang of tumor-associated neutrophils

21 January 2018

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Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression

21 January 2018

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Cancer-related inflammation

21 January 2018

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Macrophage plasticity and polarization in tissue repair and remodelling

21 January 2018

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Neutralizing tumor-promoting chronic inflammation: a magic bullet?

21 January 2018

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RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly

21 January 2018

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Distinct role of macrophages in different tumor microenvironments

21 January 2018

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Tumor-associated macrophages: functional diversity, clinical significance, and open questions

21 January 2018

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Monocytes and macrophages in cancer: development and functions

21 January 2018

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Tumor associated macrophages and neutrophils in cancer

21 January 2018

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Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population.

21 January 2018

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The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages

21 January 2018

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Role of macrophages in tumour progression.

21 January 2018

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Collaborating with the enemy: function of macrophages in the development of neoplastic disease.

21 January 2018

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Regulation of hematopoietic and leukemic stem cells by the immune system.

21 January 2018

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Trophic macrophages in development and disease

21 January 2018

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Resident macrophages influence stem cell activity in the mammary gland

21 January 2018

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Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages.

21 January 2018

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Mesenchymal stem cell-educated macrophages: a novel type of alternatively activated macrophages

21 January 2018

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Macrophages in multiple myeloma: emerging concepts and therapeutic implications

21 January 2018

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

21 January 2018

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Interaction of acute leukemia cells with the bone marrow microenvironment: implications for control of minimal residual disease

21 January 2018

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Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

21 January 2018

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Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

21 January 2018

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Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

21 January 2018

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CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress

21 January 2018

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Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.

21 January 2018

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Targeting of CD44 eradicates human acute myeloid leukemic stem cells

21 January 2018

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CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice

21 January 2018

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CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

21 January 2018

1 reference

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Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Signal regulatory protein alpha negatively regulates beta2 integrin-mediated monocyte adhesion, transendothelial migration and phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Signal regulatory proteins in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

A novel MyD-1 (SIRP-1alpha) signaling pathway that inhibits LPS-induced TNFalpha production by monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

CD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors

21 January 2018

1 reference

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c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Crosstalk between colon cancer cells and macrophages via inflammatory mediators and CD47 promotes tumour cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Hypothesis: Tim-3/galectin-9, a new pathway for leukemia stem cells survival by promoting expansion of myeloid-derived suppressor cells and differentiating into tumor-associated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

TIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

The expression of Tim-3 in peripheral blood of ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Identification of a factor that links apoptotic cells to phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

MFG-E8 released by apoptotic endothelial cells triggers anti-inflammatory macrophage reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

EGF stimulates lamellipod extension in metastatic mammary adenocarcinoma cells by an actin-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

T lymphocytes that infiltrate tumors and atherosclerotic plaques produce heparin-binding epidermal growth factor-like growth factor and basic fibroblast growth factor: a potential pathologic role

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Macrophage plasticity and polarization: in vivo veritas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial-mesenchymal transition in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Cancer stem-like cells derived from chemoresistant tumors have a unique capacity to prime tumorigenic myeloid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Liposome mediated depletion of macrophages: an approach for fundamental studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Tumor-associated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Screening for inhibitors of microglia to reduce neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/γcnull mice model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Portal application of autologous CD133+ bone marrow cells to the liver: a novel concept to support hepatic regeneration

21 January 2018

1 reference

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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

21 January 2018

1 reference

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Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer

21 January 2018

1 reference

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Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

21 January 2018

1 reference

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Epigenetic reprogramming modulates malignant properties of human liver cancer.

21 January 2018

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Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways.

21 January 2018

1 reference

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Multiple drug resistance mechanisms in cancer

21 January 2018

1 reference

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

21 January 2018

1 reference

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ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients' outcome

21 January 2018

1 reference

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A restricted cell population propagates glioblastoma growth after chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas

21 January 2018

1 reference

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Defining the mode of tumour growth by clonal analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Macrophage biology in development, homeostasis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Inflammation and autophagy conspire to promote tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Cellular and molecular pathways linking inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Macrophage activation and polarization: nomenclature and experimental guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Macrophage activation and polarization as an adaptive component of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Exploring the full spectrum of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Secretion of epidermal growth factor by macrophages associated with breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

21 January 2018

1 reference

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An Address on the Value of Pathological Experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Cancer stem cell targeting: the next generation of cancer therapy and molecular imaging.

31 March 2020

1 reference

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Stat proteins and oncogenesis

31 March 2020

1 reference

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JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.132

Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes

31 March 2020

1 reference

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TIM-3 expression in human osteosarcoma: Correlation with the expression of epithelial-mesenchymal transition-specific biomarkers

31 March 2020

1 reference

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Local opsonization for apoptosis?

31 March 2020

1 reference

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STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion

31 March 2020

1 reference

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Cancer stem cells: the challenges ahead

31 March 2020

1 reference

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A unique role for p53 in the regulation of M2 macrophage polarization

31 March 2020

1 reference

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Transforming growth factor-alpha: an oncodevelopmental growth factor

31 March 2020

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12 December 2020

Abnormal function of the bone marrow microenvironment in chronic myelogenous leukemia: role of malignant stromal macrophages.

1 reference

12 December 2020

The role of CSF-1 in normal and neoplastic breast physiology

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12 December 2020

Heat shock response in gastrointestinal tract

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12 December 2020

CD163+ tumor-associated macrophages correlated with poor prognosis and cancer stem cells in oral squamous cell carcinoma

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12 December 2020

A module map showing conditional activity of expression modules in cancer

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12 December 2020