(Q38908528)

English

Vaccine Targeting of Subdominant CD8+ T Cell Epitopes Increases the Breadth of the T Cell Response upon Viral Challenge, but May Impair Immediate Virus Control

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Vaccine Targeting of Subdominant CD8+ T Cell Epitopes Increases the Breadth of the T Cell Response upon Viral Challenge, but May Impair Immediate Virus Control (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Karen N Nielsen

object named as

Karen N Nielsen

4

0 references

Jan Pravsgaard Christensen

object named as

Jan P Christensen

5

0 references

Allan Randrup Thomsen

object named as

Allan R Thomsen

6

0 references

author name string

Maria A Steffensen

1

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Louise H Pedersen

2

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Marie L Jahn

3

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

language of work or name

0 references

publication date

12 February 2016

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Journal of Immunology

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

196

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

2666-2676

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Confronting complexity: real-world immunodominance in antiviral CD8+ T cell responses

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

CD8+ T cell efficacy in vaccination and disease

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T cell populations

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Impacts of Avidity and Specificity on the Antiviral Efficiency of HIV-1-Specific CTL

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Epitope dominance, competition and T cell affinity maturation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Immunodomination in the evolution of dominant epitope-specific CD8+ T lymphocyte responses in simian immunodeficiency virus-infected rhesus monkeys

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

T cells compete for access to antigen-bearing antigen-presenting cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

CTL ontogeny and viral escape: implications for HIV-1 vaccine design

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Epitope Escape Mutation and Decay of Human Immunodeficiency Virus Type 1-Specific CTL Responses

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Targeting of non-dominant antigens as a vaccine strategy to broaden T-cell responses during chronic viral infection

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

MHC Class II-Associated Invariant Chain Linkage of Antigen Dramatically Improves Cell-Mediated Immunity Induced by Adenovirus Vaccines

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Enhanced and sustained CD8+ T cell responses with an adenoviral vector-based hepatitis C virus vaccine encoding NS3 linked to the MHC class II chaperone protein invariant chain

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: it is even bigger than we thought

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Vaccination with an adenoviral vector encoding the tumor antigen directly linked to invariant chain induces potent CD4+T-cell-independent CD8+T-cell-mediated tumor control

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Adenovirus-based vaccine against Listeria monocytogenes: extending the concept of invariant chain linkage

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Addition of a prominent epitope affects influenza A virus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Class I gene regulation of haplotype preference may influence antiviral immunity in vivo.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

CTL escape viral variants. I. Generation and molecular characterization

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

The combination of major histocompatibility complex (MHC) and non-MHC genes influences murine lymphocytic choriomeningitis virus pathogenesis

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Qualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: not as bad as their reputation.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Effector-like CD8⁺ T cells in the memory population mediate potent protective immunity

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Vaccination against lymphocytic choriomeningitis virus infection in MHC class II-deficient mice

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Cutting edge: rapid in vivo killing by memory CD8 T cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Distinct roles of cytolytic effector molecules for antigen-restricted killing by CTL in vivo

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Viral immune evasion due to persistence of activated T cells without effector function

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Subdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Subdominant CD8 T-cell epitopes account for protection against cytomegalovirus independent of immunodomination

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Quality and Vaccine Efficacy of CD4+ T Cell Responses Directed to Dominant and Subdominant Epitopes in ESAT-6 from Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1502018

21 January 2018

Identifiers

10.4049/JIMMUNOL.1502018

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

ResearchGate publication ID

0 references

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