(Q38920722)

7 September 2017

title

Biodegradable polymeric micelles encapsulated JK184 suppress tumor growth through inhibiting Hedgehog signaling pathway (English)

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7 September 2017

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Nannan Zhang

1

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7 September 2017

Shichang Liu

2

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7 September 2017

Ning Wang

3

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7 September 2017

Senyi Deng

4

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7 September 2017

Linjiang Song

5

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7 September 2017

Qinjie Wu

6

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7 September 2017

Lei Liu

7

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7 September 2017

Weijun Su

8

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7 September 2017

Yuquan Wei

9

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7 September 2017

Yongmei Xie

10

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7 September 2017

Changyang Gong

11

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7 September 2017

language of work or name

English

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publication date

1 February 2015

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7 September 2017

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7 September 2017

volume

7

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7 September 2017

issue

6

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7 September 2017

page(s)

2609-2624

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The Hedgehog and Wnt signalling pathways in cancer

7 September 2017

cites work

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https://api.crossref.org/works/10.1039%2FC4NR06300G

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

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Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

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Gli1 maintains cell survival by up-regulating IGFBP6 and Bcl-2 through promoter regions in parallel manner in pancreatic cancer cells

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A small-molecule antagonist of the hedgehog signaling pathway.

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Converse conformational control of smoothened activity by structurally related small molecules

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Anti-tumor activity and safety evaluation of fisetin-loaded methoxy poly(ethylene glycol)-poly(epsilon-caprolactone) nanoparticles

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Biodegradable polymeric micelle-encapsulated quercetin suppresses tumor growth and metastasis in both transgenic zebrafish and mouse models

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Curcumin-encapsulated MePEG/PCL diblock copolymeric micelles: a novel controlled delivery vehicle for cancer therapy

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Preparation and characterization of methoxy poly(ethylene glycol)/poly(epsilon-caprolactone) amphiphilic block copolymeric nanospheres for tumor-specific folate-mediated targeting of anticancer drugs

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The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling

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Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

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Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles

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Small molecule modulation of Smoothened activity

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Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves radiation tumor therapy

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Acetyl-11-keto-beta-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis

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Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene

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Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy.

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Caspase-3 drives apoptosis in pancreatic cancer cells after treatment with gemcitabine

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Shh signaling and pancreatic cancer: implications for therapy?

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Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer

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Pancreatic cancer stem cells.

21 January 2018

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Tumour stem cells and drug resistance

21 January 2018

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Cancer stem cells and self-renewal.

21 January 2018

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GLI transcription factors: mediators of oncogenic Hedgehog signalling

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The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis.

21 January 2018

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Tumorigenesis and the angiogenic switch

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The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

21 January 2018

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21 January 2018

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Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect

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Nanoscale drug delivery systems for enhanced drug penetration into solid tumors: current progress and opportunities

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21 January 2018

Identifiers

DOI

10.1039/C4NR06300G

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7 September 2017

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