(Q38936478)

7 September 2017

title

Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase (English)

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7 September 2017

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Biao Ma

1

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7 September 2017

Yan Chen

2

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7 September 2017

Ling Chen

3

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7 September 2017

Hongcheng Cheng

4

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7 September 2017

Chenglong Mu

5

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7 September 2017

Jie Li

6

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7 September 2017

Ruize Gao

7

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7 September 2017

Changqian Zhou

8

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7 September 2017

Lei Cao

9

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7 September 2017

Jinhua Liu

10

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7 September 2017

Yushan Zhu

11

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7 September 2017

Quan Chen

12

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7 September 2017

Shian Wu

13

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7 September 2017

language of work or name

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1 December 2014

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7 September 2017

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7 September 2017

volume

17

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7 September 2017

issue

1

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7 September 2017

page(s)

95-103

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https://scigraph.springernature.com/pub.10.1038/ncb3073

7 September 2017

exact match

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cites work

The hippo signaling pathway in development and cancer

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The Hippo pathway and human cancer.

21 January 2018

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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

21 January 2018

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

21 January 2018

1 reference

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

21 January 2018

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The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

1 reference

Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

21 January 2018

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

21 January 2018

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Elucidation of a universal size-control mechanism in Drosophila and mammals

21 January 2018

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 January 2018

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Molecular alterations of h-warts/LATS1 tumor suppressor in human soft tissue sarcoma

21 January 2018

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The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor

21 January 2018

1 reference

Hypoxia-inducible factors in physiology and medicine

21 January 2018

1 reference

Exploiting tumour hypoxia in cancer treatment

21 January 2018

1 reference

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

21 January 2018

1 reference

The ubiquitin ligase Siah2 and the hypoxia response

21 January 2018

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Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors

21 January 2018

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An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response.

21 January 2018

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Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah

21 January 2018

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Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH

21 January 2018

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Siah: a promising anticancer target

21 January 2018

1 reference

Characterization of human homologs of the Drosophila seven in absentia (sina) gene

21 January 2018

1 reference

Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity

21 January 2018

1 reference

Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts

21 January 2018

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Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth

21 January 2018

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Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis

21 January 2018

1 reference

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

21 January 2018

1 reference

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

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Filling out the Hippo pathway

21 January 2018

1 reference

Herding Hippos: regulating growth in flies and man.

21 January 2018

1 reference

Hippo signaling: growth control and beyond

21 January 2018

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Integration of intercellular signaling through the Hippo pathway

21 January 2018

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Hypoxia signalling in cancer and approaches to enforce tumour regression

21 January 2018

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Downregulation of the large tumor suppressor 2 (LATS2/KPM) gene is associated with poor prognosis in acute lymphoblastic leukemia

21 January 2018

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12 December 2020

Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors

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12 December 2020

Frequent polymorphic changes but rare tumor specific mutations of the LATS2 gene on 13q11-12 in esophageal squamous cell carcinoma

1 reference

12 December 2020

Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer

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12 December 2020

Identifiers

DOI

10.1038/NCB3073

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Dimensions Publication ID

7 September 2017

1043713225

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