(Q38943508)

7 September 2017

Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma (English)

1 reference

7 September 2017

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Francesca Rapino

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Manuela Antonioli

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Gian Maria Fimia

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

P Giglio

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

B Conti

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

P E Lovat

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

M Piacentini

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

F Ciccosanti

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

publication date

7 November 2014

1 reference

Cell Death & Differentiation

7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

946-958

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/cdd.2014.183

7 June 2020

exact match

0 references

cites work

Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.

1 reference

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p53 status determines the role of autophagy in pancreatic tumour development

9 September 2017

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Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma.

9 September 2017

1 reference

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Why is autophagy important for melanoma? Molecular mechanisms and therapeutic implications

9 September 2017

1 reference

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A JNK-mediated autophagy pathway that triggers c-IAP degradation and necroptosis for anticancer chemotherapy.

9 September 2017

1 reference

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Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations

9 September 2017

1 reference

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The pathology of melanoma

9 September 2017

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Deconvoluting the context-dependent role for autophagy in cancer

9 September 2017

1 reference

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Stress management at the ER: regulators of ER stress-induced apoptosis

9 September 2017

1 reference

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Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice

9 September 2017

1 reference

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Genetic alterations of PTEN in human melanoma

9 September 2017

1 reference

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BRAFV600E: implications for carcinogenesis and molecular therapy

9 September 2017

1 reference

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Targeting BRAF for patients with melanoma.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy

9 September 2017

1 reference

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Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.

9 September 2017

1 reference

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Regulation of autophagy in mammals and its interplay with apoptosis.

9 September 2017

1 reference

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Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy.

9 September 2017

1 reference

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Autophagy in cutaneous malignant melanoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

BRAF signaling and targeted therapies in melanoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

A role for ubiquitin in selective autophagy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress.

9 September 2017

1 reference

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Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma

9 September 2017

1 reference

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Toward a molecular classification of melanoma.

9 September 2017

1 reference

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Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

9 September 2017

1 reference

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9 September 2017

1 reference

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Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.

9 September 2017

1 reference

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

9 September 2017

1 reference

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The role of the unfolded protein response in tumour development: friend or foe?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma

9 September 2017

1 reference

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A trip to the ER: coping with stress

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

V599EB-RAF is an oncogene in melanocytes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

Ki-67, Bcl-2 and p53 expression in primary and metastatic melanoma.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423179

21 August 2018

Identifiers

DOI

10.1038/CDD.2014.183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361077%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

25361077

1 reference