(Q38953166)

7 September 2017

Pathophysiology of Ebola Virus Infection: Current Challenges and Future Hopes (English)

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7 September 2017

Orthoebolavirus zairense

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author name string

Andrea Rivera

series ordinal

1

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PubMed ID

27622648

7 September 2017

Ilhem Messaoudi

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2

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PubMed ID

27622648

7 September 2017

language of work or name

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30 March 2015

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7 September 2017

ACS Infectious Diseases

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7 September 2017

1

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7 September 2017

5

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7 September 2017

186-197

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Human asymptomatic Ebola infection and strong inflammatory response

7 September 2017

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12 December 2020

Apoptosis induced in vitro and in vivo during infection by Ebola and Marburg viruses

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12 December 2020

Lymphocyte death in a mouse model of Ebola virus infection

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12 December 2020

A single phosphorodiamidate morpholino oligomer targeting VP24 protects rhesus monkeys against lethal Ebola virus infection

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12 December 2020

Mucosal immunization of cynomolgus macaques with the VSVDeltaG/ZEBOVGP vaccine stimulates strong ebola GP-specific immune responses

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12 December 2020

Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

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12 December 2020

Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses

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12 December 2020

Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses

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12 December 2020

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

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12 December 2020

How Ebola virus infects cells

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12 December 2020

A practical treatment for patients with Ebola virus disease

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12 December 2020

Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates

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12 December 2020

Nitric oxide induces cell death by regulating anti-apoptotic BCL-2 family members

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12 December 2020

Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease.

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12 December 2020

Small molecule inhibitors of ER α-glucosidases are active against multiple hemorrhagic fever viruses

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12 December 2020

Dose-response study of recombinant factor VIIa/tissue factor inhibitor recombinant nematode anticoagulant protein c2 in prevention of postoperative venous thromboembolism in patients undergoing total knee replacement.

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12 December 2020

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

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12 December 2020

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

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12 December 2020

Safety and pharmacokinetic profiles of phosphorodiamidate morpholino oligomers with activity against ebola virus and marburg virus: results of two single-ascending-dose studies

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12 December 2020

US signs contract with ZMapp maker to accelerate development of the Ebola drug

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12 December 2020

3-deazaneplanocin A induces massively increased interferon-alpha production in Ebola virus-infected mice

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12 December 2020

Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses

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12 December 2020

Emergency postexposure vaccination with vesicular stomatitis virus-vectored Ebola vaccine after needlestick

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12 December 2020

Ebola hemorrhagic fever in Kikwit, Democratic Republic of the Congo: clinical observations in 103 patients

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12 December 2020

The cytoprotective enzyme heme oxygenase-1 suppresses Ebola virus replication

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12 December 2020

Effective post-exposure treatment of Ebola infection

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12 December 2020

Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection

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12 December 2020

Emergence of Zaire Ebola Virus Disease in Guinea

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12 December 2020

Filoviruses: Interactions with the host cell

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12 December 2020

Passive transfer of antibodies protects immunocompetent and imunodeficient mice against lethal Ebola virus infection without complete inhibition of viral replication.

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12 December 2020

Recombinant nematode anticoagulant protein c2, an inhibitor of the tissue factor/factor VIIa complex, in patients undergoing elective coronary angioplasty

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12 December 2020

Structural characterization and membrane binding properties of the matrix protein VP40 of Ebola virus

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12 December 2020

Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assay

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12 December 2020

Lethal experimental infection of rhesus monkeys with Ebola-Zaire (Mayinga) virus by the oral and conjunctival route of exposure.

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12 December 2020

Early immune responses accompanying human asymptomatic Ebola infections

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12 December 2020

Release of viral glycoproteins during Ebola virus infection

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12 December 2020

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

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12 December 2020

Inhibition of Marburg virus protein expression and viral release by RNA interference

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12 December 2020

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

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12 December 2020

Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: cellular responses, virus load, and nitric oxide levels

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12 December 2020

Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling

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12 December 2020

Filovirus assembly and budding

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12 December 2020

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

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12 December 2020

Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome

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12 December 2020

Update: Ebola virus disease epidemic--West Africa, November 2014.

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12 December 2020

Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection

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12 December 2020

Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys

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12 December 2020

A systematic screen of FDA-approved drugs for inhibitors of biological threat agents

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12 December 2020

The enantiomers of the 1',6'-isomer of neplanocin A: synthesis and antiviral properties

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12 December 2020

Management of accidental exposure to Ebola virus in the biosafety level 4 laboratory, Hamburg, Germany

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12 December 2020

Ebola virus infection of human PBMCs causes massive death of macrophages, CD4 and CD8 T cell sub-populations in vitro.

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12 December 2020

Inflammatory responses in Ebola virus-infected patients.

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12 December 2020

Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge

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12 December 2020

Antibodies are necessary for rVSV/ZEBOV-GP-mediated protection against lethal Ebola virus challenge in nonhuman primates

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12 December 2020

Single-injection vaccine protects nonhuman primates against infection with marburg virus and three species of ebola virus

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12 December 2020

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

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12 December 2020

Depletion of peripheral blood T lymphocytes and NK cells during the course of ebola hemorrhagic Fever in cynomolgus macaques

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12 December 2020

Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1

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12 December 2020

Identification of a broad-spectrum inhibitor of viral RNA synthesis: validation of a prototype virus-based approach

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12 December 2020

The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein

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12 December 2020

Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

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12 December 2020

Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients

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12 December 2020

Antiviral activity of a small-molecule inhibitor of filovirus infection

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12 December 2020

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs

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12 December 2020

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

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12 December 2020

Molecular determinants of Ebola virus virulence in mice

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12 December 2020

Identification of a small-molecule entry inhibitor for filoviruses

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12 December 2020

Recombinant human activated protein C for the postexposure treatment of Ebola hemorrhagic fever

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12 December 2020

Recombinant vesicular stomatitis virus vector mediates postexposure protection against Sudan Ebola hemorrhagic fever in nonhuman primates

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12 December 2020

Three of the four nucleocapsid proteins of Marburg virus, NP, VP35, and L, are sufficient to mediate replication and transcription of Marburg virus-specific monocistronic minigenomes

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12 December 2020

Advanced antisense therapies for postexposure protection against lethal filovirus infections.

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12 December 2020

Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys

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12 December 2020

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA

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12 December 2020

Infection and activation of monocytes by Marburg and Ebola viruses

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12 December 2020

Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation

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12 December 2020

A broad-spectrum antiviral targeting entry of enveloped viruses

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12 December 2020

Ebola haemorrhagic fever

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12 December 2020

Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis

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12 December 2020

Protective efficacy of neutralizing monoclonal antibodies in a nonhuman primate model of Ebola hemorrhagic fever

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12 December 2020

HSPA5 is an essential host factor for Ebola virus infection

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12 December 2020

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

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12 December 2020

Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily

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12 December 2020

FGI-104: a broad-spectrum small molecule inhibitor of viral infection

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12 December 2020

Pre- and postexposure prophylaxis of Ebola virus infection in an animal model by passive transfer of a neutralizing human antibody

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12 December 2020

Postexposure protection of guinea pigs against a lethal ebola virus challenge is conferred by RNA interference

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12 December 2020

Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents

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12 December 2020

CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates

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12 December 2020

Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients. International Scientific and Technical Committee

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12 December 2020

Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells

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12 December 2020

Haematological, biochemical and coagulation changes in mice, guinea-pigs and monkeys infected with a mouse-adapted variant of Ebola Zaire virus

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12 December 2020

Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies

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12 December 2020

The lack of maturation of Ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains

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12 December 2020

Host response dynamics following lethal infection of rhesus macaques with Zaire ebolavirus

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12 December 2020

FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.

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12 December 2020

TNF-induced signaling in apoptosis

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12 December 2020

Role of reactive oxygen species (ROS) in apoptosis induction

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12 December 2020

A new Ebola virus nonstructural glycoprotein expressed through RNA editing

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12 December 2020

A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever

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12 December 2020

Ebola virus disease in West Africa--the first 9 months of the epidemic and forward projections

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12 December 2020

Identification of an antioxidant small-molecule with broad-spectrum antiviral activity.

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12 December 2020

Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection

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12 December 2020

Assessment of a vesicular stomatitis virus-based vaccine by use of the mouse model of Ebola virus hemorrhagic fever

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12 December 2020

Interferon-β therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever

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12 December 2020

Case fatality rates of Ebola virus diseases: a meta-analysis of World Health Organization data

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12 December 2020

Antigenic subversion: a novel mechanism of host immune evasion by Ebola virus

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12 December 2020

Development of a broad-spectrum antiviral with activity against Ebola virus

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12 December 2020

Potential vaccines and post-exposure treatments for filovirus infections

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12 December 2020

Ebola GP-specific monoclonal antibodies protect mice and guinea pigs from lethal Ebola virus infection

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12 December 2020

Vesicular stomatitis virus-based ebola vaccine is well-tolerated and protects immunocompromised nonhuman primates

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12 December 2020

Pathogenesis of experimental Ebola virus infection in guinea pigs

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12 December 2020

The clinically approved drugs amiodarone, dronedarone and verapamil inhibit filovirus cell entry

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12 December 2020

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses

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12 December 2020

Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery

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12 December 2020

Apoptosis in fatal Ebola infection. Does the virus toll the bell for immune system?

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12 December 2020

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.

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12 December 2020

Identifiers

DOI

10.1021/ID5000426

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7 September 2017

0 references

1 reference

PubMed ID

27622648