(Q38957210)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Pang-hsien Tu

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Yun-Ru Chen

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Yu-Sheng Fang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Yu-Jen Chang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Patricia Kao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Rima Woods

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Pan-Hsien Kuo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Cheng-Chun Wu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Jhih-Ying Liao

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Shih-Chieh Chou

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Vinson Lin

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Lee-Way Jin

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Hanna S Yuan

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Irene H Cheng

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

language of work or name

English

0 references

publication date

12 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

4824

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/ncomms5824

16 February 2020

exact match

0 references

cites work

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TAR DNA-binding protein 43 in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Frontotemporal dementia: clinicopathological correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

21 January 2018

Frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP-43 proteinopathies: neurodegenerative protein misfolding diseases without amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

A 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Amyloid fibrils: abnormal protein assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP-43: an emerging new player in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Structural insights into TDP-43 in nucleic-acid binding and domain interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Induction of amyloid fibrils by the C-terminal fragments of TDP-43 in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Aberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

The truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Structural transformation of the amyloidogenic core region of TDP-43 protein initiates its aggregation and cytoplasmic inclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Delineation of the core aggregation sequences of TDP-43 C-terminal fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Kinetics of interaction of partially folded proteins with a hydrophobic dye: evidence that molten globule character is maximal in early folding intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Amyloid beta-protein assembly and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

The E. coli CsgB nucleator of curli assembles to β-sheet oligomers that alter the CsgA fibrillization mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Preparation and characterization of neurotoxic tau oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Concurrence of TDP-43, tau and alpha-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Prion-like properties of pathological TDP-43 aggregates from diseased brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

How to measure and predict the molar absorption coefficient of a protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: stable trimer or tetramer formation by Abeta42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Kinetic traps in the folding/unfolding of procaspase-1 CARD domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

inferred from DOI database lookup

7 January 2021

based on heuristic

Folding stability of amyloid-beta 40 monomer is an important determinant of the nucleation kinetics in fibrillization

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5824

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS5824

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25215604%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 February 2020

ADS bibcode

2014NatCo...5.4824F

0 references

0 references

1 reference