(Q34685007)

English

Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation (English)

1 reference

Europe PubMed Central

3 August 2017

author name string

Wei-Ting Chen

1

1 reference

Europe PubMed Central

3 August 2017

Yi-Hung Liao

2

1 reference

Europe PubMed Central

3 August 2017

Hui-Ming Yu

3

1 reference

Europe PubMed Central

3 August 2017

Irene H Cheng

4

1 reference

Europe PubMed Central

3 August 2017

Yun-Ru Chen

5

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

7 January 2011

1 reference

Europe PubMed Central

3 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

3 August 2017

286

1 reference

Europe PubMed Central

3 August 2017

11

1 reference

Europe PubMed Central

3 August 2017

9646-9656

1 reference

Europe PubMed Central

3 August 2017

Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Aluminum in the diet and Alzheimer's disease: from current epidemiology to possible disease-modifying treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Fibrillar oligomers nucleate the oligomerization of monomeric amyloid beta but do not seed fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Demonstration of aluminum in amyloid fibers in the cores of senile plaques in the brains of patients with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Alzheimer's disease, metal ions and metal homeostatic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Molecular toxicity of aluminium in relation to neurodegeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Amyloid beta-protein assembly and Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Amyloid precursor protein trafficking, processing, and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Binding of zinc(II) and copper(II) to the full-length Alzheimer's amyloid-beta peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Potential pathogenic role of beta-amyloid(1-42)-aluminum complex in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

High-resolution NMR studies of the zinc-binding site of the Alzheimer's amyloid beta-peptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Molecular structure of amyloid fibrils: insights from solid-state NMR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

On the nucleation of amyloid beta-protein monomer folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

The neurobiology of zinc in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

The metallobiology of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Synaptically released zinc: physiological functions and pathological effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

NMR studies in aqueous solution fail to identify significant conformational differences between the monomeric forms of two Alzheimer peptides with widely different plaque-competence, A beta(1-40)(ox) and A beta(1-42)(ox).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

New insights on how metals disrupt amyloid beta-aggregation and their effects on amyloid-beta cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Copper, iron and zinc in Alzheimer's disease senile plaques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

ZnT-3, a putative transporter of zinc into synaptic vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Rapid induction of Alzheimer A beta amyloid formation by zinc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Fluorescence Probes for Structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059000

7 July 2018

Neuroscience: Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Blood-based neurochemical diagnosis of vascular dementia: a pilot study.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Amyloid beta 38, 40, and 42 species in cerebrospinal fluid: more of the same?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Copper binding to the amyloid-beta (Abeta) peptide associated with Alzheimer's disease: folding, coordination geometry, pH dependence, stoichiometry, and affinity of Abeta-(1-28): insights from a range of complementary spectroscopic techniques

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Identifying the minimal copper- and zinc-binding site sequence in amyloid-beta peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

N-Terminal deletions modify the Cu2+ binding site in amyloid-beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Metal binding in amyloid beta-peptides shows intra- and inter-peptide coordination modes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Solution 1H NMR investigation of Zn2+ and Cd2+ binding to amyloid-beta peptide (Abeta) of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Metallothionein III is reduced in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Metal ions differentially influence the aggregation and deposition of Alzheimer's beta-amyloid on a solid template.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Zinc-amyloid beta interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Influence of multiple metal ions on beta-amyloid aggregation and dissociation on a solid surface.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Aluminum-triggered structural modifications and aggregation of beta-amyloids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Effects of aluminum on the neurotoxicity of primary cultured neurons and on the aggregation of beta-amyloid protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Protection against amyloid beta peptide toxicity by zinc.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Kinetic traps in the folding/unfolding of procaspase-1 CARD domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: stable trimer or tetramer formation by Abeta42.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

4,4(')-Dianilino-1,1(')-binaphthyl-5,5(')-disulfonate: report on non-beta-sheet conformers of Alzheimer's peptide beta(1-40).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Early onset familial Alzheimer's disease: Mutation frequency in 31 families.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Aluminum in the Diet and Alzheimer's Disease: From Current Epidemiology to Possible Disease-Modifying Treatment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.177246

21 January 2018

Characterization of copper binding to the peptide amyloid-β(1–16) associated with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21216965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc Lowers Amyloid-β Toxicity by Selectively Precipitating Aggregation Intermediates†

1 reference

https://pubmed.ncbi.nlm.nih.gov/21216965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21216965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.177246

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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