(Q33320694)

25 July 2017

Binding of zinc(II) and copper(II) to the full-length Alzheimer's amyloid-beta peptide (English)

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25 July 2017

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Vello Tõugu

1

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author name string

Ann Karafin

series ordinal

2

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25 July 2017

Peep Palumaa

series ordinal

3

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25 July 2017

language of work or name

English

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publication date

1 March 2008

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Journal of Neurochemistry

25 July 2017

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25 July 2017

104

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25 July 2017

1249-1259

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25 July 2017

5

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Release of endogenous Zn2+ from brain tissue during activity.

25 July 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

The metallobiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

High-resolution NMR studies of the zinc-binding site of the Alzheimer's amyloid beta-peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Synaptically released zinc: physiological functions and pathological effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Concentrations of extracellular free zinc (pZn)e in the central nervous system during simple anesthetization, ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Structural and thermodynamical properties of CuII amyloid-beta16/28 complexes associated with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Evidence for release of copper in the brain: depolarization-induced release of newly taken-up 67copper

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Methods for studying synaptosomal copper release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Stimulation-induced uptake and release of zinc in hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Redox reactions of copper complexes formed with different beta-amyloid peptides and their neuropathological [correction of neuropathalogical] relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Nerve endings from rat brain tissue release copper upon depolarization. A possible role in regulating neuronal excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

N-Terminal deletions modify the Cu2+ binding site in amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Oxidative processes in Alzheimer's disease: the role of abeta-metal interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Copper and iron disorders of the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Metal binding modes of Alzheimer's amyloid beta-peptide in insoluble aggregates and soluble complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Metal ion-dependent effects of clioquinol on the fibril growth of an amyloid {beta} peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Aluminum-triggered structural modifications and aggregation of beta-amyloids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

NMDA receptor activation mediates copper homeostasis in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Cu(II) complexation by "non-coordinating" N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid (HEPES buffer).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Solution 1H NMR investigation of Zn2+ and Cd2+ binding to amyloid-beta peptide (Abeta) of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Copper binding to the amyloid-beta (Abeta) peptide associated with Alzheimer's disease: folding, coordination geometry, pH dependence, stoichiometry, and affinity of Abeta-(1-28): insights from a range of complementary spectroscopic techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

C-terminal domain of the membrane copper transporter Ctr1 from Saccharomyces cerevisiae binds four Cu(I) ions as a cuprous-thiolate polynuclear cluster: sub-femtomolar Cu(I) affinity of three proteins involved in copper trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.05061.X

10.1111/J.1471-4159.2007.05061.X

21 January 2018

Identifiers

DOI

1 reference

release_h2bscrpaebgbhl2qesjogyeyp4

25 July 2017

1 reference

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24 November 2022

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