(Q38962182)

8 September 2017

The unfolded protein response mediates reversible tau phosphorylation induced by metabolic stress (English)

1 reference

8 September 2017

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jeroen Hoozemans

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Wiep Scheper

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

J M van der Harg

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

A Nölle

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

R Zwart

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

E S van Haastert

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

A M Strijkstra

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

publication date

28 August 2014

1 reference

8 September 2017

Cell Death and Disease

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

e1393

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

31 May 2020

copyright license

start time

1 August 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4454326/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice

1 reference

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9 September 2017

1 reference

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Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions

9 September 2017

1 reference

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Endoplasmic reticulum dysfunction in neurological disease

9 September 2017

1 reference

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Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (P

9 September 2017

1 reference

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Clinical and biomarker changes in dominantly inherited Alzheimer's disease

9 September 2017

1 reference

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Sustained translational repression by eIF2α-P mediates prion neurodegeneration

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Endoplasmic reticulum: the unfolded protein response is tangled in neurodegeneration.

9 September 2017

1 reference

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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

The unfolded protein response: from stress pathway to homeostatic regulation

9 September 2017

1 reference

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Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

9 September 2017

1 reference

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Neuronal activity regulates the regional vulnerability to amyloid-β deposition

9 September 2017

1 reference

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The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation

9 September 2017

1 reference

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Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Mammalian hibernation: differential gene expression and novel application of epigenetic controls

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Differential regulation of dynein and kinesin motor proteins by tau

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Tau phosphorylation in Alzheimer's disease: pathogen or protector?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Physiology: hibernation in a tropical primate

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Unfolded protein response activates glycogen synthase kinase-3 via selective lysosomal degradation.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Staging of Alzheimer's disease-related neurofibrillary changes

14 September 2017

1 reference

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Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Hibernation model of tau phosphorylation in hamsters: selective vulnerability of cholinergic basal forebrain neurons - implications for Alzheimer's disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Tau pathology as a cause and consequence of the UPR.

17 June 2018

1 reference

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Comparing brain amyloid deposition, glucose metabolism, and atrophy in mild cognitive impairment with and without a family history of dementia.

21 August 2018

1 reference

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Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes.

21 August 2018

1 reference

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Decreased cortical glucose metabolism in converters from CDR 0.5 to Alzheimer's disease in a community: the Osaki-Tajiri Project

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Insulin dysfunction induces in vivo tau hyperphosphorylation through distinct mechanisms.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

The unfolded protein response is activated in Alzheimer's disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Increased risk of type 2 diabetes in Alzheimer disease

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Limbic hypometabolism in Alzheimer's disease and mild cognitive impairment

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4454326

Rapid synthesis of biotin-, digoxigenin-, trinitrophenyl-, and fluorochrome-labeled tyramides and their application for In situ hybridization using CARD amplification

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25165879

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Endoplasmic reticulum stress features are prominent in Alzheimer disease but not in prion diseases in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25165879

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2014.354

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25165879%20AND%20SRC:MED&resulttype=core&format=json