(Q38965192)

8 September 2017

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title

Ursolic Acid and Chronic Disease: An Overview of UA's Effects On Prevention and Treatment of Obesity and Cancer (English)

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8 September 2017

author name string

Anna M Mancha-Ramirez

series ordinal

1

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8 September 2017

Thomas J Slaga

series ordinal

2

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8 September 2017

language of work or name

English

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publication date

1 January 2016

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Advances in Experimental Medicine and Biology

8 September 2017

number of pages

22

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based on heuristic

inferred from page(s)

published in

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8 September 2017

volume

928

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8 September 2017

page(s)

75-96

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Molecular targets of nutraceuticals derived from dietary spices: potential role in suppression of inflammation and tumorigenesis

8 September 2017

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Nitric oxide-induced activation of the AMP-activated protein kinase α2 subunit attenuates IκB kinase activity and inflammatory responses in endothelial cells

21 January 2018

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Dietary energy balance modulates prostate cancer progression in Hi-Myc mice

21 January 2018

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The molecular mechanisms underpinning the therapeutic properties of oleanolic acid, its isomer and derivatives for type 2 diabetes and associated complications

21 January 2018

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21 January 2018

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21 January 2018

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Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate

21 January 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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UP12, a novel ursolic acid derivative with potential for targeting multiple signaling pathways in hepatocellular carcinoma.

21 January 2018

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Activation of AMP-activated protein kinase, inhibition of pyruvate dehydrogenase activity, and redistribution of substrate partitioning mediate the acute insulin-sensitizing effects of troglitazone in skeletal muscle cells

21 January 2018

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Dietary lipids and calorie restriction affect mammary tumor incidence and gene expression in mouse mammary tumor virus/v-Ha-ras transgenic mice

21 January 2018

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Obesity and prostate cancer: making sense out of apparently conflicting data

21 January 2018

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Mechanisms of hepatic fibrogenesis

21 January 2018

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Ursolic acid and oleanolic acid suppress preneoplastic lesions induced by 1,2-dimethylhydrazine in rat colon

21 January 2018

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Antidiabetic and antioxidant effects of oleanolic acid from Ligustrum lucidum Ait in alloxan-induced diabetic rats

21 January 2018

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Sirtuins as potential targets for metabolic syndrome

21 January 2018

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Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

21 January 2018

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Cranberry phytochemicals: Isolation, structure elucidation, and their antiproliferative and antioxidant activities

21 January 2018

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Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

21 January 2018

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Pentacyclic triterpene distribution in various plants - rich sources for a new group of multi-potent plant extracts.

21 January 2018

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Ursolic acid enhances the cellular immune system and pancreatic beta-cell function in streptozotocin-induced diabetic mice fed a high-fat diet

21 January 2018

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Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas).

21 January 2018

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Resveratrol and P-glycoprotein inhibitors enhance the anti-skin cancer effects of ursolic acid.

21 January 2018

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Ursolic acid and resveratrol synergize with chloroquine to reduce melanoma cell viability

21 January 2018

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Insulin-mimetic and insulin-sensitizing activities of a pentacyclic triterpenoid insulin receptor activator

21 January 2018

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NF-kappaB as a critical link between inflammation and cancer

21 January 2018

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Effect of maternal obesity on insulin action in male adult offspring rats.

21 January 2018

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Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention

21 January 2018

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Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease

21 January 2018

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Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and I kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro.

21 January 2018

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Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin–nicotinamide-induced diabetic mice

21 January 2018

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Targeting apoptosis pathways in cancer by Chinese medicine

21 January 2018

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LC-MS determination and pharmacokinetic studies of ursolic acid in rat plasma after administration of the traditional chinese medicinal preparation Lu-Ying extract

21 January 2018

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Novel antihepatotoxic principles of Solanum incanum.

21 January 2018

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Oleanolic acid derivative NPLC441 potently stimulates glucose transport in 3T3-L1 adipocytes via a multi-target mechanism

21 January 2018

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Nuclear factor-kappa B is upregulated in colorectal cancer

21 January 2018

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Ursolic Acid provides kidney protection in diabetic rats

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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In vitro hyperresponsiveness to tumor necrosis factor-alpha contributes to adipokine dysregulation in omental adipocytes of obese subjects

21 January 2018

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Comparative expression of NFkappaB proteins in melanocytes of normal skin vs. benign intradermal naevus and human metastatic melanoma biopsies

21 January 2018

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Oleanolic acid, a natural triterpenoid improves blood glucose tolerance in normal mice and ameliorates visceral obesity in mice fed a high-fat diet.

21 January 2018

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Ethnobotany, phytochemistry and pharmacology of the genus Caragana used in traditional Chinese medicine.

21 January 2018

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Caloric restriction and L-carnitine administration improves insulin sensitivity in patients with impaired glucose metabolism.

21 January 2018

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Fast food fever: reviewing the impacts of the Western diet on immunity

21 January 2018

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Cellular and molecular mechanisms in liver fibrogenesis

21 January 2018

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Diet, inflammation, and glycemic control in type 2 diabetes: an integrative review of the literature

21 January 2018

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Protective effects of ursolic acid and oleanolic acid in leukemic cells

21 January 2018

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Anti-inflammatory effects of methyl ursolate obtained from a chemically derived crude extract of apple peels: potential use in rheumatoid arthritis.

21 January 2018

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Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells

21 January 2018

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Plant-derived anticancer agents

21 January 2018

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Body mass index, weight change, and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort

21 January 2018

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AMPK, insulin resistance, and the metabolic syndrome

21 January 2018

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Terpenoids: natural inhibitors of NF-kappaB signaling with anti-inflammatory and anticancer potential

21 January 2018

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Targeting multiple signal pathways by chemopreventive agents for cancer prevention and therapy

21 January 2018

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Chronic non-communicable diseases, the European Chronic Disease Alliance--and cancer

21 January 2018

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Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies.

21 January 2018

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Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer

21 January 2018

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Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice

21 January 2018

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In vitro and in vivo anticancer activity evaluation of ursolic acid derivatives

21 January 2018

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21 January 2018

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Metabolic syndrome and its association with colorectal cancer: a review

21 January 2018

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Angiogenic factors are elevated in overweight and obese individuals.

21 January 2018

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Cardiovascular, antihyperlipidemic and antioxidant effects of oleanolic and ursolic acids in experimental hypertension

21 January 2018

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Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

21 January 2018

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NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon?

21 January 2018

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Hyrtiosal, a PTP1B inhibitor from the marine sponge Hyrtios erectus, shows extensive cellular effects on PI3K/AKT activation, glucose transport, and TGFbeta/Smad2 signaling.

21 January 2018

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Inflammatory mechanisms in the regulation of insulin resistance

21 January 2018

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The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation

21 January 2018

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Ursolic acid protects diabetic mice against monocyte dysfunction and accelerated atherosclerosis

21 January 2018

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Adipose tissue: a motor for the inflammation associated with obesity

21 January 2018

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Targeting the AMPK pathway for the treatment of Type 2 diabetes

21 January 2018

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Antidiabetic effect of oleanolic acid: a promising use of a traditional pharmacological agent

21 January 2018

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Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts

21 January 2018

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Transcriptional factors that promote formation of white adipose tissue

21 January 2018

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Adiponectin--a key adipokine in the metabolic syndrome

21 January 2018

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Ursolic Acid--A Pentacyclic Triterpenoid with a Wide Spectrum of Pharmacological Activities

21 January 2018

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Peroxisome proliferator-activated receptors gamma and alpha agonists stimulate cardiac glucose uptake via activation of AMP-activated protein kinase.

21 January 2018

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IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway

21 January 2018

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Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer

21 January 2018

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Synthesis and Biological Evaluation of Novel Ursolic acid Derivatives as Potential Anticancer Prodrugs.

21 January 2018

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Green tea consumption and colorectal cancer risk: a report from the Shanghai Men's Health Study

21 January 2018

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Ursolic acid, a naturally occurring triterpenoid, suppresses migration and invasion of human breast cancer cells by modulating c-Jun N-terminal kinase, Akt and mammalian target of rapamycin signaling

21 January 2018

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Research progress of ursolic acid's anti-tumor actions

21 January 2018

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Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake

21 January 2018

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AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p300.

21 January 2018

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Active ingredients from natural botanicals in the treatment of obesity

21 January 2018

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Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells

21 January 2018

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Role of AMP-activated protein kinase in mechanism of metformin action

21 January 2018

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Obesity and cancer: Pathophysiological and biological mechanisms

21 January 2018

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Dietary factors and breast cancer risk: a case control study among a population in Southern France

21 January 2018

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Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

31 March 2020

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Obesity and the environment: where do we go from here?

31 March 2020

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Case-control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables

31 March 2020

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Progress in cancer chemoprevention: development of diet-derived chemopreventive agents

31 March 2020

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Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice

31 March 2020

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The effects of 10 triterpenoid compounds on experimental liver injury in mice

31 March 2020

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Catalase overexpression impairs TNF-alpha induced NF-kappaB activation and sensitizes MCF-7 cells against TNF-alpha

31 March 2020

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Inhibition of protein tyrosine phosphatase 1B by diterpenoids isolated from Acanthopanax koreanum

31 March 2020

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Calorie restriction reduced blood pressure in obesity hypertensives by improvement of autonomic nerve activity and insulin sensitivity.

31 March 2020

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Adipocyte differentiation and gene expression

31 March 2020

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Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches

31 March 2020

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Ursolic Acid, a Pentacyclic Triterpene from Sambucus australis, Prevents Abdominal Adiposity in Mice Fed a High-Fat Diet

31 March 2020

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Nuclear factor kappa B (NF-κB): a novel cause for diabetes, coronary artery disease and cancer initiation and promotion?

31 March 2020

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Anti-inflammatory activity of oleanolic acid in rats and mice

31 March 2020

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10.1007/978-3-319-41334-1_4

31 March 2020

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