(Q38969138)

8 September 2017

title

Sequestosome 1/p62 facilitates HER2-induced mammary tumorigenesis through multiple signaling pathways (English)

1 reference

8 September 2017

X Cai-McRae

1

1 reference

8 September 2017

H Zhong

series ordinal

2

1 reference

8 September 2017

V Karantza

series ordinal

3

1 reference

8 September 2017

language of work or name

English

0 references

publication date

4 August 2014

1 reference

8 September 2017

1 reference

8 September 2017

volume

34

1 reference

8 September 2017

issue

23

1 reference

8 September 2017

page(s)

2968-2977

1 reference

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

HER2 status in pure ductal carcinoma in situ and in the intraductal and invasive components of invasive ductal carcinoma determined by fluorescence in situ hybridization and immunohistochemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

ErbB receptors and signaling pathways in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Reduced expression of PTEN correlates with breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

The complex world of WNT receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

p62/SQSTM1/A170: physiology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

p62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

The double-edged sword of autophagy modulation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

p62 is a key regulator of nutrient sensing in the mTORC1 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Subtle variations in Pten dose determine cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

p62 modulates Akt activity via association with PKCzeta in neuronal survival and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Sequestosome 1/p62, a scaffolding protein, is a newly identified partner of IRS-1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Akt stimulates aerobic glycolysis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

A mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

Induction of autophagy by amino-acid deprivation in perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.244

The HER2 (c-erbB-2) oncogene is frequently amplified in in situ carcinomas of the breast

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25088198

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.244

1 reference

Dimensions Publication ID

8 September 2017

1015653542

0 references

1 reference