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Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk
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title
Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk
(English)
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main subject
autophagy
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author
Paloma Ordóñez-Morán
object named as
Paloma Ordóñez-Morán
series ordinal
4
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Alexander Greenhough
object named as
Alexander Greenhough
series ordinal
11
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Jon D Lane
object named as
Jon D Lane
series ordinal
3
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Karim Malik
object named as
Karim Malik
series ordinal
9
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Ann C Williams
object named as
Ann C Williams
series ordinal
2
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author name string
Katy J Petherick
series ordinal
1
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Joerg Huelsken
series ordinal
5
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Tracey J Collard
series ordinal
6
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Helena J M Smartt
series ordinal
7
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Jennifer Batson
series ordinal
8
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Chris Paraskeva
series ordinal
10
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language of work or name
English
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publication date
3 July 2013
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published in
The EMBO Journal
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volume
32
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page(s)
1903-16
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issue
13
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describes a project that uses
ImageJ
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Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3981178/fullTextXML
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inferred from PubMed Central ID database lookup
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cites work
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reference URL
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19 March 2017
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
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19 March 2017
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
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PubMed Central
reference URL
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retrieved
19 March 2017
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
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19 March 2017
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
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PubMed Central
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19 March 2017
The human Frizzled 6 (HFz6) acts as a negative regulator of the canonical Wnt. beta-catenin signaling cascade
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19 March 2017
The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
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19 March 2017
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
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19 March 2017
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19 March 2017
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19 March 2017
Structural basis for sorting mechanism of p62 in selective autophagy
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19 March 2017
Autophagy fights disease through cellular self-digestion
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19 March 2017
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
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19 March 2017
Functional interaction between beta-catenin and FOXO in oxidative stress signaling
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19 March 2017
Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis.
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19 March 2017
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19 March 2017
Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia
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19 March 2017
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7 April 2017
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
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7 April 2017
Autophagy in mammalian development and differentiation
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7 April 2017
A role for ubiquitin in selective autophagy
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7 April 2017
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
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7 April 2017
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7 April 2017
Linking colorectal cancer to Wnt signaling
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7 April 2017
A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress
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27 September 2017
E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells
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27 September 2017
Sequestosome 1/p62: across diseases
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27 September 2017
KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.
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27 September 2017
β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells
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27 September 2017
β-catenin is dynamically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway.
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27 September 2017
The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming
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27 September 2017
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981178
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27 September 2017
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
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PubMed Central
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27 September 2017
The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981178
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27 September 2017
The double-edged sword of autophagy modulation in cancer
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27 September 2017
Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.
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27 September 2017
The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981178
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27 September 2017
Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981178
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27 September 2017
Protein-protein interaction assays: eliminating false positive interactions
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981178
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27 September 2017
Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981178
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27 September 2017
beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3981178
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27 September 2017
A Wnt-fall for gene regulation: repression
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FEMBOJ.2013.123
retrieved
21 January 2018
Identifiers
DOI
10.1038/EMBOJ.2013.123
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
868574
OpenCitations bibliographic resource ID
868574
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
868574
PMCID
3981178
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
868574
PubMed ID
23736261
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
868574
ResearchGate publication ID
237056344
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