(Q38978675)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24989122%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

A role for DNA polymerase θ in the timing of DNA replication (English)

1 reference

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21 March 2020

1

1 reference

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21 March 2020

Jean-Charles Cadoret

3

1 reference

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21 March 2020

Etienne Schwob

5

1 reference

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21 March 2020

author name string

Laure Guitton-Sert

2

1 reference

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21 March 2020

Marjorie Drac

4

1 reference

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21 March 2020

Giuseppe Baldacci

6

1 reference

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21 March 2020

Christophe Cazaux

7

1 reference

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21 March 2020

Jean-Sébastien Hoffmann

8

1 reference

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21 March 2020

language of work or name

English

0 references

publication date

3 July 2014

1 reference

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21 March 2020

published in

Nature Communications

1 reference

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21 March 2020

volume

5

1 reference

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21 March 2020

page(s)

4285

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Promiscuous DNA synthesis by human DNA polymerase θ

21 March 2020

cites work

1 reference

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POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells

21 January 2018

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Human DNA polymerase theta possesses 5'-dRP lyase activity and functions in single-nucleotide base excision repair in vitro

21 January 2018

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Low-fidelity DNA synthesis by human DNA polymerase theta.

21 January 2018

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DNA polymerases and somatic hypermutation of immunoglobulin genes

21 January 2018

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DNA polymerase theta purified from human cells is a high-fidelity enzyme

21 January 2018

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Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes

21 January 2018

1 reference

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DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes

21 January 2018

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The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation

21 January 2018

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Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.

21 January 2018

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Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage

21 January 2018

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Single-nucleotide base excision repair DNA polymerase activity in C. elegans in the absence of DNA polymerase β

21 January 2018

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Lack of DNA polymerase theta (POLQ) radiosensitizes bone marrow stromal cells in vitro and increases reticulocyte micronuclei after total-body irradiation

21 January 2018

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A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown

21 January 2018

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Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells

21 January 2018

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Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila

21 January 2018

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Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions

21 January 2018

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Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.

21 January 2018

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High-efficiency bypass of DNA damage by human DNA polymerase Q

21 January 2018

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DNA polymerase theta (POLQ) can extend from mismatches and from bases opposite a (6-4) photoproduct

21 January 2018

1 reference

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DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients.

21 January 2018

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DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability

21 January 2018

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A 'DNA replication' signature of progression and negative outcome in colorectal cancer

21 January 2018

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Aberrant expression of alternative DNA polymerases: a source of mutator phenotype as well as replicative stress in cancer

21 January 2018

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DNA replication in eukaryotic cells

21 January 2018

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Establishing the program of origin firing during S phase in fission Yeast.

21 January 2018

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The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase.

21 January 2018

1 reference

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Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint.

21 January 2018

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Space and time in the nucleus: developmental control of replication timing and chromosome architecture

21 January 2018

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Global reorganization of replication domains during embryonic stem cell differentiation

21 January 2018

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Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells

21 January 2018

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Rif1 regulates the replication timing domains on the human genome

21 January 2018

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Rif1 is a global regulator of timing of replication origin firing in fission yeast

21 January 2018

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USF binding sequences from the HS4 insulator element impose early replication timing on a vertebrate replicator.

21 January 2018

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Evidence for sequential and increasing activation of replication origins along replication timing gradients in the human genome

21 January 2018

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Isochores and the evolutionary genomics of vertebrates

21 January 2018

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Replication timing, chromosomal bands, and isochores

21 January 2018

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Unraveling cell type-specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs.

21 January 2018

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New insights into replication origin characteristics in metazoans

21 January 2018

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Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase

21 January 2018

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A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation

21 January 2018

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Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint

21 January 2018

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DNA polymerase POLQ and cellular defense against DNA damage

21 January 2018

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A link among DNA replication, recombination, and gene expression revealed by genetic and genomic analysis of TEBICHI gene of Arabidopsis thaliana

21 January 2018

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Arabidopsis TEBICHI, with helicase and DNA polymerase domains, is required for regulated cell division and differentiation in meristems

21 January 2018

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The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm

21 January 2018

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A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice.

21 January 2018

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DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis

21 January 2018

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Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication

21 January 2018

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DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation.

21 January 2018

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Overexpression of POLQ confers a poor prognosis in early breast cancer patients

21 January 2018

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DNA polymerase theta is preferentially expressed in lymphoid tissues and upregulated in human cancers

21 January 2018

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Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia

21 January 2018

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Signatures of mutation and selection in the cancer genome

21 January 2018

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21 January 2018

Chromosome fragile sites

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Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

21 January 2018

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

21 January 2018

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Dynamic molecular combing: stretching the whole human genome for high-resolution studies.

21 January 2018

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Use of DNA combing for studying DNA replication in vivo in yeast and mammalian cells.

21 January 2018

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Cohesin organizes chromatin loops at DNA replication factories.

21 January 2018

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Replication of the Chicken β-Globin Locus: Early-Firing Origins at the 5′ HS4 Insulator and the ρ- and βA-Globin Genes Show Opposite Epigenetic Modifications

21 January 2018

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Galaxy: a platform for interactive large-scale genome analysis

21 January 2018

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DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Isochores and replication time zones: a perfect match

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5285

inferred from DOI database lookup

7 January 2021

based on heuristic

Modeling genome-wide replication kinetics reveals a mechanism for regulation of replication timing

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5285