(Q38981617)

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BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma

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scholarly article

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Europe PubMed Central

8 September 2017

BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma (English)

1 reference

Europe PubMed Central

8 September 2017

Frédéric Blanchard

10

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9 June 2020

Dominique Heymann

11

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9 June 2020

author name string

Bérengère Gobin

1

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9 June 2020

Marc Baud' Huin

2

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9 June 2020

François Lamoureux

3

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9 June 2020

Benjamin Ory

4

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9 June 2020

Céline Charrier

5

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9 June 2020

Rachel Lanel

6

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9 June 2020

Séverine Battaglia

7

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9 June 2020

Françoise Redini

8

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9 June 2020

Frédéric Lezot

9

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9 June 2020

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publication date

30 June 2014

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8 September 2017

International Journal of Cancer

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9 June 2020

136

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9 June 2020

4

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9 June 2020

784-796

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9 June 2020

Osteosarcoma (osteogenic sarcoma).

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Current therapeutic strategies and novel approaches in osteosarcoma

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Emerging drugs for high-grade osteosarcoma

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

The emerging mechanisms of isoform-specific PI3K signalling

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Structural basis for activation and inhibition of class I phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

PIK3CA mutations in advanced cancers: characteristics and outcomes

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Clinical development of phosphatidylinositol 3-kinase inhibitors for cancer treatment

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Alteration of cellular behavior and response to PI3K pathway inhibition by culture in 3D collagen gels

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

MicroRNA-221 induces cell survival and cisplatin resistance through PI3K/Akt pathway in human osteosarcoma

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Inhibition of c-Met activation sensitizes osteosarcoma cells to cisplatin via suppression of the PI3K-Akt signaling

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

High-throughput genotyping in osteosarcoma identifies multiple mutations in phosphoinositide-3-kinase and other oncogenes

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Studies of bone and soft-tissue tumours induced in rats with radioactive cerium chloride

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Inhibition of lung metastasis of osteosarcoma cell line POS-1 transplanted into mice by thigh ligation

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Pericyte-like progenitors show high immaturity and engraftment potential as compared with mesenchymal stem cells.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Proteoglycans and osteolysis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Targeting sarcomas: novel biological agents and future perspectives

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Updating progress in sarcoma therapy with mTOR inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

NVP-BEZ235, a dual PI3K/mTOR inhibitor, inhibits osteosarcoma cell proliferation and tumor development in vivo with an improved survival rate

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

The impact of tumor microenvironment on cancer treatment and its modulation by direct and indirect antivascular strategies

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Regulation of angiogenesis by PI3K signaling networks

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Correlation between clinical outcome and growth factor pathway expression in osteogenic sarcoma

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Prognostic relevance of increased angiogenesis in osteosarcoma.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Therapeutic approach of primary bone tumours by bisphosphonates.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Class IA phosphatidylinositol 3-kinase regulates osteoclastic bone resorption through protein kinase B-mediated vesicle transport.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Dysregulation of bone remodeling by imatinib mesylate.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Correlating phosphatidylinositol 3-kinase inhibitor efficacy with signaling pathway status: in silico and biological evaluations

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29040

21 January 2018

Identifiers

10.1002/IJC.29040

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961790%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24961790%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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