(Q38982139)

English

Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies (English)

1 reference

Europe PubMed Central

8 September 2017

multiple sclerosis

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3

object named as

Ralf Gold

1 reference

Europe PubMed Central

8 September 2017

author name string

Sreeja Gopal

1

1 reference

Europe PubMed Central

8 September 2017

Alvydas Mikulskis

2

1 reference

Europe PubMed Central

8 September 2017

Robert J Fox

4

1 reference

Europe PubMed Central

8 September 2017

Katherine T Dawson

5

1 reference

Europe PubMed Central

8 September 2017

Lakshmi Amaravadi

6

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Europe PubMed Central

8 September 2017

language of work or name

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publication date

1 January 2017

1 reference

Europe PubMed Central

8 September 2017

Multiple Sclerosis Journal

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Europe PubMed Central

8 September 2017

1352458517690617

1 reference

Europe PubMed Central

8 September 2017

Multiple sclerosis

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Disease-modifying drugs for multiple sclerosis: current and future aspects

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS.

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke.

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Fumaric acid and its esters: an emerging treatment for multiple sclerosis with antioxidative mechanism of action

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2.

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Detection of fumarate-glutathione adducts in the portal vein blood of rats: evidence for rapid dimethylfumarate metabolism

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Pharmacokinetics of oral fumarates in healthy subjects.

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid esters

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Targeting glutathione by dimethylfumarate protects against experimental malaria by enhancing erythrocyte cell membrane scrambling.

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Detection of metabolites of fumaric acid esters in human urine: implications for their mode of action

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Ethanol-induced HO-1 and NQO1 are differentially regulated by HIF-1alpha and Nrf2 to attenuate inflammatory cytokine expression

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

BRG1 interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Effects of fumarates on circulating and CNS myeloid cells in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1177%2F1352458517690617

21 January 2018

Identifiers

10.1177/1352458517690617

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

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