(Q38982380)

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RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24952599%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis (English)

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21 March 2020

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colorectal cancer

1 reference

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inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

cancer metastasis

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Mathias Dahlmann

1

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21 March 2020

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Anna Okhrimenko

2

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21 March 2020

Patrick Marcinkowski

3

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21 March 2020

Marc Osterland

4

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21 March 2020

Pia Herrmann

5

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21 March 2020

Janice Smith

6

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21 March 2020

Claus W Heizmann

7

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21 March 2020

Peter M Schlag

8

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21 March 2020

Ulrike Stein

9

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21 March 2020

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1 May 2014

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21 March 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24952599%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

5

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21 March 2020

10

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21 March 2020

3220-3233

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Europe PubMed Central

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21 March 2020

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4102805/fullTextXML

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Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody

1 reference

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1 reference

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9 September 2017

Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation.

1 reference

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9 September 2017

S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis

1 reference

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9 September 2017

Asymmetric Mode of Ca2+-S100A4 Interaction with Nonmuscle Myosin IIA Generates Nanomolar Affinity Required for Filament Remodeling

1 reference

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9 September 2017

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9 September 2017

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1 reference

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9 September 2017

S100A4-induced cell motility and metastasis is restricted by the Wnt/β-catenin pathway inhibitor calcimycin in colon cancer cells

1 reference

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9 September 2017

Alternative splicing of RAGE: roles in biology and disease

1 reference

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9 September 2017

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1 reference

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9 September 2017

Intervening in β-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis

1 reference

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9 September 2017

Diagnostic and prognostic value of metastasis inducer S100A4 transcripts in plasma of colon, rectal, and gastric cancer patients

1 reference

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9 September 2017

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102805

9 September 2017

S100A8/A9 activate key genes and pathways in colon tumor progression

1 reference

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9 September 2017

S100A4 over-expression underlies lymph node metastasis and poor prognosis in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102805

9 September 2017

RAGE Signaling Significantly Impacts Tumorigenesis and Hepatic Tumor Growth in Murine Models of Colorectal Carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102805

9 September 2017

Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB

1 reference

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9 September 2017

S100A4 and metastasis: a small actor playing many roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102805

9 September 2017

Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 protein

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9 September 2017

Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102805

9 September 2017

Association between body mass index and colorectal neoplasia at follow-up colonoscopy: a pooling study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102805

9 September 2017

Binding of S100 proteins to RAGE: an update.

1 reference

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9 September 2017

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis

1 reference

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9 September 2017

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102805

9 September 2017

Activation of NF-kappaB by extracellular S100A4: analysis of signal transduction mechanisms and identification of target genes

1 reference

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9 September 2017

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

1 reference

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9 September 2017

Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging

1 reference

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Receptor for advanced glycation endproducts: a multiligand receptor magnifying cell stress in diverse pathologic settings

1 reference

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9 September 2017

Anti-S100A4 antibody suppresses metastasis formation by blocking stroma cell invasion.

1 reference

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9 September 2017

A tumor hypoxic niche protects human colon cancer stem cells from chemotherapy

1 reference

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High mobility group box 1 released from necrotic cells enhances regrowth and metastasis of cancer cells that have survived chemotherapy

1 reference

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9 September 2017

Hypoxia enhances colon cancer migration and invasion through promotion of epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102805

9 September 2017

Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer

1 reference

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9 September 2017

Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-{kappa}B.

1 reference

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Effect of hypoxia-inducible factor 1-α on Survivin in colorectal cancer

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1 reference

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RAGE activation by S100P in colon cancer stimulates growth, migration, and cell signaling pathways

1 reference

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1 reference

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RAGE expression and AGE-induced MAP kinase activation in Caco-2 cells

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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4 November 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24952599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24952599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24952599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24952599

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based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of S100A4 mRNA and protein expression in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24952599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.18632/ONCOTARGET.1908

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24952599%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24952599%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24952599%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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