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RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.
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Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
title
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
main subject
necroptosis
1 reference
based on heuristic
inferred from title
author
Susana Orozco
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
Stephen Tait
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
Douglas R. Green
series ordinal
8
1 reference
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Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
author name string
N Yatim
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2
1 reference
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Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
M R Werner
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3
1 reference
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Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
H Tran
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
S Y Gunja
series ordinal
5
1 reference
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Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
M L Albert
series ordinal
7
1 reference
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Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
A Oberst
series ordinal
9
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Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
publication date
6 June 2014
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Europe PubMed Central
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4158689
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
volume
21
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
page(s)
1511-1521
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
issue
10
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
exact match
https://scigraph.springernature.com/pub.10.1038/cdd.2014.76
0 references
cites work
Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling
1 reference
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9 September 2017
Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
1 reference
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PubMed Central
reference URL
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9 September 2017
Survival function of the FADD-CASPASE-8-cFLIP(L) complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Pick your poison: the Ripoptosome, a cell death platform regulating apoptosis and necroptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
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PubMed Central
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9 September 2017
cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Molecular mechanisms of necroptosis: an ordered cellular explosion
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9 September 2017
Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation
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PubMed Central
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9 September 2017
Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
TNF-alpha induces two distinct caspase-8 activation pathways
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Identification of RIP1 kinase as a specific cellular target of necrostatins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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9 September 2017
FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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14 September 2017
Virus inhibition of RIP3-dependent necrosis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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14 September 2017
Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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14 September 2017
Activation of procaspases by FK506 binding protein-mediated oligomerization
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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14 September 2017
A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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17 June 2018
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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17 June 2018
DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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21 August 2018
RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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21 August 2018
Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
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21 August 2018
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4158689
retrieved
21 August 2018
Identifiers
DOI
10.1038/CDD.2014.76
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
Fatcat ID
release_3zfqjqp7mndx3lvdy3hy2r5gcy
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Fatcat
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https://api.fatcat.wiki/v0/release/3zfqjqp7mndx3lvdy3hy2r5gcy
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
4158689
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
PubMed ID
24902904
1 reference
stated in
Europe PubMed Central
PMCID
4158689
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24902904%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 March 2020
ResearchGate publication ID
262928060
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