(Q38993830)

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Asymmetric dimethyl arginine induces pulmonary vascular dysfunction via activation of signal transducer and activator of transcription 3 and stabilization of hypoxia-inducible factor 1-alpha

scientific article published on 17 June 2015

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Europe PubMed Central

PubMed publication ID

8 September 2017

Asymmetric dimethyl arginine induces pulmonary vascular dysfunction via activation of signal transducer and activator of transcription 3 and stabilization of hypoxia-inducible factor 1-alpha (English)

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8 September 2017

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13 June 2020

Gabriela Ambrozova

4

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13 June 2020

Jaroslav Kadlec

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Jaroslav Kadlec

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13 June 2020

Zdenka Kuchtova

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Zdenka Kuchtova

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13 June 2020

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Lukas Kubala

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13 June 2020

Michaela Pekarova

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Michaela Pekarova

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13 June 2020

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Hana Kolarova

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13 June 2020

Anna Klinke

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13 June 2020

Anna Cerna

6

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13 June 2020

Maria Trundova

8

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13 June 2020

Lenka Sindlerova Svihalkova

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13 June 2020

Radek Kuchta

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13 June 2020

Antonin Lojek

12

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13 June 2020

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17 June 2015

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8 September 2017

Vascular Pharmacology

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13 June 2020

73

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13 June 2020

138-148

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13 June 2020

Mechanisms of disease: pulmonary arterial hypertension.

1 reference

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7 January 2021

An epidemiological study of pulmonary arterial hypertension.

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Early detection of pulmonary arterial hypertension in systemic sclerosis: A French nationwide prospective multicenter study

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Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach

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Pulmonary hypertension diagnosed by right heart catheterisation in sickle cell disease

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Biosynthesis and action of nitric oxide in mammalian cells

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Enzymatic function of nitric oxide synthases

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7 January 2021

Nitric oxide synthases: structure, function and inhibition

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The endothelial ADMA/NO pathway in hypoxia-related chronic respiratory diseases.

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7 January 2021

Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension

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7 January 2021

Plasma asymmetric dimethylarginine levels are increased in neonates with bronchopulmonary dysplasia-associated pulmonary hypertension

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7 January 2021

Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection

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7 January 2021

Elevated homocysteine and asymmetric dimethyl arginine levels in pulmonary hypertension associated with congenital heart disease

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7 January 2021

Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function.

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7 January 2021

Asymmetric dimethylarginine impairs fibrinolytic activity in human umbilical vein endothelial cells via p38 MAPK and NF-κB pathways

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7 January 2021

Asymmetric dimethylarginine does not inhibit arginase activity and is pro-proliferative in pulmonary endothelial cells

1 reference

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7 January 2021

Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: role of mitochondrial dysfunction

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7 January 2021

Mechanism of cellular oxidation stress induced by asymmetric dimethylarginine

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7 January 2021

The ADMA/DDAH pathway is a critical regulator of endothelial cell motility

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7 January 2021

Vaspin increases nitric oxide bioavailability through the reduction of asymmetric dimethylarginine in vascular endothelial cells

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7 January 2021

Asymmetrical dimethylarginine inhibits shear stress-induced nitric oxide release and dilation and elicits superoxide-mediated increase in arteriolar tone

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7 January 2021

Asymmetric dimethylarginine and whole blood viscosity in renal failure

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7 January 2021

Increased asymmetric dimethylarginine (ADMA) dimethylaminohydrolase (DDAH) activity in childhood hypercholesterolemia type II

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7 January 2021

Protein Arginine Methyltransferases (PRMTs): promising targets for the treatment of pulmonary disorders.

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7 January 2021

miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.

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7 January 2021

Role of the PRMT-DDAH-ADMA axis in the regulation of endothelial nitric oxide production

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7 January 2021

Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase

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7 January 2021

Asymmetric dimethylarginine regulates the lipopolysaccharide-induced nitric oxide production in macrophages by suppressing the activation of NF-kappaB and iNOS expression.

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7 January 2021

Chronic hypoxia-induced upregulation of store-operated and receptor-operated Ca2+ channels in pulmonary arterial smooth muscle cells: a novel mechanism of hypoxic pulmonary hypertension

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7 January 2021

Tumor necrosis factor-alpha-induced TRPC1 expression amplifies store-operated Ca2+ influx and endothelial permeability

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7 January 2021

Vascular remodeling process in pulmonary arterial hypertension, with focus on miR-204 and miR-126 (2013 Grover Conference series).

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7 January 2021

Emerging translational approaches to target STAT3 signalling and its impact on vascular disease

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7 January 2021

Activation of hypoxia-inducible factor-1 in pulmonary arterial smooth muscle cells by endothelin-1.

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7 January 2021

Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes.

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7 January 2021

Signal transducer and activator of transcription 3alpha and specificity protein 1 interact to upregulate intercellular adhesion molecule-1 in ischemic-reperfused myocardium and vascular endothelium.

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Cholinergic agonists regulate JAK2/STAT3 signaling to suppress endothelial cell activation

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MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression

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Classical transient receptor potential channel 1 in hypoxia-induced pulmonary hypertension.

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Arginine de novo and nitric oxide production in disease states

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Protective effects of 10-nitro-oleic acid in a hypoxia-induced murine model of pulmonary hypertension

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The unique role of dietary L-arginine in the acceleration of peritoneal macrophage sensitivity to bacterial endotoxin

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Transcriptional repression of hypoxia-inducible factor-1 (HIF-1) by the protein arginine methyltransferase PRMT1

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Involvement of asymmetric dimethylarginine and Rho kinase in the vascular remodeling in monocrotaline-induced pulmonary hypertension

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Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis

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ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins

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Asymmetric dimethylarginine induces oxidative and nitrosative stress in murine lung epithelial cells

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Asymmetric dimethylarginine induces endothelial nitric-oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1

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Regulation of eNOS-derived superoxide by endogenous methylarginines

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