(Q39007042)

English

Triptolide synergistically enhances temozolomide-induced apoptosis and potentiates inhibition of NF-κB signaling in glioma initiating cells

scientific article published on January 2014

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Triptolide synergistically enhances temozolomide-induced apoptosis and potentiates inhibition of NF-κB signaling in glioma initiating cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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author name string

Ke Sai

1

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Europe PubMed Central

PubMed publication ID

8 September 2017

Wen-Yu Li

2

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Europe PubMed Central

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8 September 2017

Yin-Sheng Chen

3

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Europe PubMed Central

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8 September 2017

Jian Wang

4

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Europe PubMed Central

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8 September 2017

Su Guan

5

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Europe PubMed Central

PubMed publication ID

8 September 2017

Qun-Ying Yang

6

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Cheng-Cheng Guo

7

1 reference

Europe PubMed Central

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8 September 2017

Yong-Gao Mou

8

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Wei-Ping Li

9

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Europe PubMed Central

PubMed publication ID

8 September 2017

Zhong-Ping Chen

10

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PubMed publication ID

8 September 2017

publication date

1 January 2014

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8 September 2017

The American Journal of Chinese Medicine

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8 September 2017

42

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8 September 2017

2

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8 September 2017

485-503

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Europe PubMed Central

PubMed publication ID

8 September 2017

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

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Chemoresistance of glioblastoma cancer stem cells--much more complex than expected

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Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas

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Vasculogenic mimicry-potential target for glioblastoma therapy: an in vitro and in vivo study.

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Triptolide circumvents drug-resistant effect and enhances 5-fluorouracil antitumor effect on KB cells.

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

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Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

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Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries

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21 January 2018

Cancer stem cells and glioma

1 reference

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21 January 2018

NF-κB and the link between inflammation and cancer

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21 January 2018

CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009.

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Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity

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21 January 2018

High-throughput chemical screens identify disulfiram as an inhibitor of human glioblastoma stem cells

1 reference

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21 January 2018

Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice

1 reference

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21 January 2018

X-linked Inhibitor of Apoptosis: A Chemoresistance Factor or a Hollow Promise

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21 January 2018

The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy

1 reference

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21 January 2018

Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts

1 reference

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21 January 2018

Expression of nuclear factor-kappaB in human astrocytomas: relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival.

1 reference

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21 January 2018

Triptolide-mediated cell death in neuroblastoma occurs by both apoptosis and autophagy pathways and results in inhibition of nuclear factor-kappa B activity

1 reference

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21 January 2018

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

1 reference

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21 January 2018

Synergistic anticancer activity of triptolide combined with cisplatin enhances apoptosis in gastric cancer in vitro and in vivo

1 reference

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21 January 2018

The effect of triptolide on apoptosis of glioblastoma multiforme (GBM) cells

1 reference

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21 January 2018

Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase

1 reference

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21 January 2018

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

1 reference

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21 January 2018

Triptolide induces the expression of miR-142-3p: a negative regulator of heat shock protein 70 and pancreatic cancer cell proliferation

1 reference

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21 January 2018

Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3beta with p53.

1 reference

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21 January 2018

Glioblastoma cancer stem-like cells: implications for pathogenesis and treatment

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21 January 2018

Triptolide cooperates with chemotherapy to induce apoptosis in acute myeloid leukemia cells.

1 reference

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21 January 2018

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens

1 reference

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21 January 2018

Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway

1 reference

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21 January 2018

NFkappaB signaling in carcinogenesis and as a potential molecular target for cancer therapy

1 reference

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21 January 2018

Triptolide inhibits Bcr-Abl transcription and induces apoptosis in STI571-resistant chronic myelogenous leukemia cells harboring T315I mutation

1 reference

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21 January 2018

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

1 reference

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21 January 2018

A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells

1 reference

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21 January 2018

Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells

1 reference

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Triptolide simultaneously induces reactive oxygen species, inhibits NF-kappaB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines

1 reference

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21 January 2018

Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding

1 reference

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21 January 2018

Triptolide inhibits transcription factor NF-kappaB and induces apoptosis of multiple myeloma cells

1 reference

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21 January 2018

NFκB inhibitors induce cell death in glioblastomas.

1 reference

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21 January 2018

Triptolide inhibits proliferation and invasion of malignant glioma cells.

1 reference

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Triptolide with potential medicinal value for diseases of the central nervous system

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Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms

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Triptolide cooperates with Cisplatin to induce apoptosis in gemcitabine-resistant pancreatic cancer.

1 reference

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21 January 2018

Identifiers

10.1142/S0192415X14500323

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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