(Q43940962)

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Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway

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scholarly article

1 reference

Europe PubMed Central

28 November 2017

Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway (English)

1 reference

Europe PubMed Central

28 November 2017

1 reference

based on heuristic

inferred from title

author name string

Ke Sai

1

1 reference

Europe PubMed Central

28 November 2017

Shuzhen Wang

2

1 reference

Europe PubMed Central

28 November 2017

Veerakumar Balasubramaniyan

3

1 reference

Europe PubMed Central

28 November 2017

Charles Conrad

4

1 reference

Europe PubMed Central

28 November 2017

Frederick F Lang

5

1 reference

Europe PubMed Central

28 November 2017

Kenneth Aldape

6

1 reference

Europe PubMed Central

28 November 2017

Slawomir Szymanski

7

1 reference

Europe PubMed Central

28 November 2017

Izabela Fokt

8

1 reference

Europe PubMed Central

28 November 2017

Atreyi Dasgupta

9

1 reference

Europe PubMed Central

28 November 2017

Timothy Madden

10

1 reference

Europe PubMed Central

28 November 2017

Su Guan

11

1 reference

Europe PubMed Central

28 November 2017

Zhongping Chen

12

1 reference

Europe PubMed Central

28 November 2017

W K Alfred Yung

13

1 reference

Europe PubMed Central

28 November 2017

Waldemar Priebe

14

1 reference

Europe PubMed Central

28 November 2017

Howard Colman

15

1 reference

Europe PubMed Central

28 November 2017

publication date

17 January 2012

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Europe PubMed Central

28 November 2017

Journal of Neuro-Oncology

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Europe PubMed Central

28 November 2017

107

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Europe PubMed Central

28 November 2017

3

1 reference

Europe PubMed Central

28 November 2017

487-501

1 reference

Europe PubMed Central

28 November 2017

https://scigraph.springernature.com/pub.10.1007/s11060-011-0786-z

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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21 January 2018

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

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21 January 2018

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

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21 January 2018

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

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21 January 2018

Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis

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21 January 2018

Tie2-mediated multidrug resistance in malignant gliomas is associated with upregulation of ABC transporters

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STATs and gene regulation

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21 January 2018

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21 January 2018

The role of STATs in transcriptional control and their impact on cellular function

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21 January 2018

Signal transducer and activator of transcription 3 is a key regulator of keratinocyte survival and proliferation following UV irradiation.

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21 January 2018

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

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21 January 2018

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

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21 January 2018

Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex.

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Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

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Stat proteins and oncogenesis

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21 January 2018

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

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21 January 2018

Activation state EGFR and STAT-3 as prognostic markers in resected non-small cell lung cancer.

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21 January 2018

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

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21 January 2018

Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

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21 January 2018

The transcriptional network for mesenchymal transformation of brain tumours.

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21 January 2018

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0786-Z

21 January 2018

STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells

1 reference

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21 January 2018

Stat3 activation is required for the growth of U87 cell-derived tumours in mice

1 reference

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21 January 2018

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

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21 January 2018

Inhibition of p-STAT3 enhances IFN-alpha efficacy against metastatic melanoma in a murine model.

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21 January 2018

Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death

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Glioma-associated cancer-initiating cells induce immunosuppression

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An implantable guide-screw system for brain tumor studies in small animals.

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21 January 2018

Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell.

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21 January 2018

Retinal stem cells in the adult mammalian eye

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21 January 2018

The MAPK signalling pathways and colorectal cancer

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21 January 2018

Identification of human brain tumour initiating cells

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21 January 2018

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0786-Z

21 January 2018

Stat3 as an oncogene

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0786-Z

21 January 2018

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0786-Z

21 January 2018

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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21 January 2018

Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy

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21 January 2018

The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas.

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21 January 2018

Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomas

1 reference

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21 January 2018

Activation of STAT3, MAPK, and AKT in malignant astrocytic gliomas: correlation with EGFR status, tumor grade, and survival.

1 reference

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21 January 2018

Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2).

1 reference

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21 January 2018

Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3.

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21 January 2018

Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis

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Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

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Notch signalling regulates stem cell numbers in vitro and in vivo

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21 January 2018

Potentiation of astrogliogenesis by STAT3-mediated activation of bone morphogenetic protein-Smad signaling in neural stem cells

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21 January 2018

Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells

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21 January 2018

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution

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A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells

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Small molecular inhibitors of p-STAT3: novel agents for treatment of primary and metastatic CNS cancers

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21 January 2018

A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo

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21 January 2018

WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells

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https://api.crossref.org/works/10.1007%2FS11060-011-0786-Z

21 January 2018

Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells

1 reference

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21 January 2018

Quantitative phosphoproteomic analysis of the STAT3/IL-6/HIF1alpha signaling network: an initial study in GSC11 glioblastoma stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS11060-011-0786-Z

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Tamoxifen stimulates the growth of cyclin D1-overexpressing breast cancer cells by promoting the activation of signal transducer and activator of transcription 3.

1 reference

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21 January 2018

Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells

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STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition

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21 January 2018

Apoptotic signaling by c-MYC.

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21 January 2018

Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

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The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition

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Apoptosis in gliomas: molecular mechanisms and therapeutic implications

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Anti-apoptosis mechanisms in malignant gliomas.

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21 January 2018

Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators

1 reference

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Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1.

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Isolation of multipotent adult stem cells from the dermis of mammalian skin

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Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells

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https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of cancer stem cells from adult glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

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based on heuristic

inferred from PubMed ID database lookup

Expression of signal transducers and activators of transcription proteins in acute myeloid leukemia blasts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain tumor stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a cancer stem cell in human brain tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

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inferred from PubMed ID database lookup

Immunology of spontaneous mammary carcinomas in mice. V. Acquired tumor resistance and enhancement in strain A mice infected with mammary tumor virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

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inferred from PubMed ID database lookup

Analyzing mitochondrial changes during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22249692

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11060-011-0786-Z

1 reference

Europe PubMed Central

28 November 2017

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https://api.fatcat.wiki/v0/release/tcyeux6h7fhzlptggurpjcs3le

24 November 2022

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Europe PubMed Central

28 November 2017

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