(Q36021584)

11 August 2017

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title

Apoptosis in gliomas: molecular mechanisms and therapeutic implications (English)

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11 August 2017

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2

Michael Weller

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11 August 2017

Joachim P Steinbach

1

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PubMed ID

15674481

11 August 2017

language of work or name

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1 November 2004

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Journal of Neuro-Oncology

11 August 2017

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11 August 2017

70

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11 August 2017

2

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11 August 2017

245-254

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https://scigraph.springernature.com/pub.10.1007/s11060-004-2753-4

11 August 2017

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cites work

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12 December 2020

Cellular stress response and apoptosis in cancer therapy.

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12 December 2020

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

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12 December 2020

Chimeric tumor suppressor 1, a p53-derived chimeric tumor suppressor gene, kills p53 mutant and p53 wild-type glioma cells in synergy with irradiation and CD95 ligand.

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12 December 2020

Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells

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12 December 2020

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

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12 December 2020

Proliferation and cell death in oligodendrogliomas.

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12 December 2020

BCL-2 promotes migration and invasiveness of human glioma cells.

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12 December 2020

Retroviral delivery and tetracycline-dependent expression of IL-1beta-converting enzyme (ICE) in a rat glioma model provides controlled induction of apoptotic death in tumor cells.

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12 December 2020

Intracerebral adenovirus-mediated p53 tumor suppressor gene therapy for experimental human glioma.

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12 December 2020

Apoptosis by retrovirus- and adenovirus-mediated gene transfer of Fas ligand to glioma cells: implications for gene therapy.

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12 December 2020

Prognostic significance of an apoptotic index and apoptosis/proliferation ratio for patients with high-grade astrocytomas

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12 December 2020

Tumor response to radiotherapy regulated by endothelial cell apoptosis

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12 December 2020

Apoptosis and cell proliferation in human neuroepithelial tumors.

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12 December 2020

Apoptosis in gliomas, and its role in their current and future treatment

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12 December 2020

Caspase-dependent chemotherapy-induced death of glioma cells requires mitochondrial cytochrome c release

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12 December 2020

Enhanced apoptosis of glioma cell lines is achieved by co-delivering FasL-GFP and TRAIL with a complex Ad5 vector

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12 December 2020

Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results

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12 December 2020

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation

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12 December 2020

Overcoming of radioresistance in human gliomas by p21WAF1/CIP1 antisense oligonucleotide.

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12 December 2020

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

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12 December 2020

Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation

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12 December 2020

PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis.

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12 December 2020

Hypoxia-induced cell death in human malignant glioma cells: energy deprivation promotes decoupling of mitochondrial cytochrome c release from caspase processing and necrotic cell death

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12 December 2020

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

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12 December 2020

The hypoxic cell: a target for selective cancer therapy--eighteenth Bruce F. Cain Memorial Award lecture.

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12 December 2020

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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12 December 2020

Growth inhibition of astrocytoma cells by farnesyl transferase inhibitors is mediated by a combination of anti-proliferative, pro-apoptotic and anti-angiogenic effects.

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12 December 2020

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

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12 December 2020

Mechanisms of apoptosis in central nervous system tumors: application to theory

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12 December 2020

Apoptosis in cerebral astrocytic tumours and its relationship to expression of the bcl-2 and p53 proteins.

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12 December 2020

Apoptosis in human primary brain tumours.

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12 December 2020

Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas.

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12 December 2020

A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents

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12 December 2020

Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas

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12 December 2020

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

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12 December 2020

Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells.

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12 December 2020

CD95-mediated apoptosis of human glioma cells: modulation by epidermal growth factor receptor activity

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12 December 2020

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

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12 December 2020

Apoptosis in glial tumors as determined by in situ nonradioactive labeling of DNA breaks.

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12 December 2020

Identification of p21 as a target of cycloheximide-mediated facilitation of CD95-mediated apoptosis in human malignant glioma cells

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12 December 2020

Predicting response to cancer chemotherapy: the role of p53.

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12 December 2020

Incidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsies.

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12 December 2020

Lethal effect of the anti-Fas antibody in mice

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12 December 2020

Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell death in primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU.

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12 December 2020

Cell death and oxidative stress in gliomas.

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12 December 2020

Attenuation of WAF1/Cip1 expression by an antisense adenovirus expression vector sensitizes glioblastoma cells to apoptosis induced by chemotherapeutic agents 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin.

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12 December 2020

Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells.

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12 December 2020

Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells

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12 December 2020

Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis.

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12 December 2020

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

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12 December 2020

Adenoviral natural born killer gene therapy for malignant glioma

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12 December 2020

FADD gene therapy for malignant gliomas in vitro and in vivo

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12 December 2020

Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand

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12 December 2020

NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells

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12 December 2020

CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release

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12 December 2020

BCL-2 family proteins modulate radiosensitivity in human malignant glioma cells

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12 December 2020

Death ligand/receptor-independent caspase activation mediates drug-induced cytotoxic cell death in human malignant glioma cells

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12 December 2020

Apoptosis in glioma cells: review and analysis of techniques used for study with focus on the laser scanning cytometer

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12 December 2020

BCL-2 family protein expression in initial and recurrent glioblastomas: modulation by radiochemotherapy

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12 December 2020

Combination therapy with irinotecan and protein kinase C inhibitors in malignant glioma

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12 December 2020

Modulation of growth and radiochemosensitivity of human malignant glioma cells by acidosis

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12 December 2020

Immunochemotherapy of malignant glioma: synergistic activity of CD95 ligand and chemotherapeutics.

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12 December 2020

Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling

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12 December 2020

Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines

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12 December 2020

Inhibition of epidermal growth factor receptor signaling protects human malignant glioma cells from hypoxia-induced cell death

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12 December 2020

Prognostic value of tumour associated antigen immunoreactivity and apoptosis in cerebral glioblastomas: an analysis of 168 cases

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12 December 2020

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

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12 December 2020

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo

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12 December 2020

Analysis of proliferation and apoptosis in brain gliomas: prognostic and clinical value

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12 December 2020

Enhanced apoptosis in pilocytic astrocytoma: a comparative study of apoptosis and proliferation in astrocytic tumors.

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12 December 2020

CD95 ligand: lethal weapon against malignant glioma?

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12 December 2020

Suppression of Rac activity induces apoptosis of human glioma cells but not normal human astrocytes.

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12 December 2020

Pharmacological rescue of mutant p53 conformation and function

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12 December 2020

CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death

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12 December 2020

APO2 ligand: a novel lethal weapon against malignant glioma?

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12 December 2020

TRAIL triggers apoptosis in human malignant glioma cells through extrinsic and intrinsic pathways.

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12 December 2020

Expression and functional activity of osteoprotegerin in human malignant gliomas

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12 December 2020

Detection of apoptotic cells in archival tissue from diffuse astrocytomas using a monoclonal antibody to single-stranded DNA.

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12 December 2020

Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin

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12 December 2020

10.1007/S11060-004-2753-4

Identifiers

DOI

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11 August 2017

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