(Q39007737)

English

Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma

scientific article published on 14 May 2014

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

Near-genomewide RNAi screening for regulators of BRAF(V600E) -induced senescence identifies RASEF, a gene epigenetically silenced in melanoma (English)

1 reference

Europe PubMed Central

8 September 2017

0 references

8

object named as

Daniel S Peeper

1 reference

Europe PubMed Central

8 September 2017

Sjoerd H van der Burg

6

object named as

Sjoerd H van der Burg

1 reference

Europe PubMed Central

8 September 2017

author name string

Joanna Kaplon

1

1 reference

Europe PubMed Central

8 September 2017

Cornelia Hömig-Hölzel

2

1 reference

Europe PubMed Central

8 September 2017

Linda Gao

3

1 reference

Europe PubMed Central

8 September 2017

Katrin Meissl

4

1 reference

Europe PubMed Central

8 September 2017

Els M E Verdegaal

5

1 reference

Europe PubMed Central

8 September 2017

Remco van Doorn

7

1 reference

Europe PubMed Central

8 September 2017

publication date

14 May 2014

1 reference

Europe PubMed Central

8 September 2017

Pigment Cell & Melanoma Research

1 reference

Europe PubMed Central

8 September 2017

27

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Europe PubMed Central

8 September 2017

640-652

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Europe PubMed Central

8 September 2017

4

1 reference

Europe PubMed Central

8 September 2017

Chemokine signaling via the CXCR2 receptor reinforces senescence

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Integrative analysis of the melanoma transcriptome

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Melanoma ex naevo: a study of the associated naevus

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Senescence in tumours: evidence from mice and humans

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Distinct sets of genetic alterations in melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

RAS and RAF mutations in banal melanocytic aggregates contiguous with primary cutaneous melanoma: clues to melanomagenesis

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Mutations of the BRAF gene in human cancer

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Genome-wide promoter methylation analysis identifies epigenetic silencing of MAPK13 in primary cutaneous melanoma.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

A landscape of driver mutations in melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Antagonistic TSC22D1 variants control BRAF(E600)-induced senescence

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Senescence of activated stellate cells limits liver fibrosis

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Senescence-messaging secretome: SMS-ing cellular stress

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

The essence of senescence

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Modeling genomic diversity and tumor dependency in malignant melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Intrinsic tumour suppression

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Epigenetic regulation identifies RASEF as a tumor-suppressor gene in uveal melanoma.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Role of autophagy in cancer

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

BRAFE600-associated senescence-like cell cycle arrest of human naevi

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Oncogene-induced cell senescence--halting on the road to cancer

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Small GTPase RAB45-mediated p38 activation in apoptosis of chronic myeloid leukemia progenitor cells

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

High frequency of BRAF mutations in nevi

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Epigenetic events in malignant melanoma.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Divorcing ARF and p53: an unsettled case

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Deregulated Akt3 activity promotes development of malignant melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Methylation profiling in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Functional identification of LRF as an oncogene that bypasses RASV12-induced senescence via upregulation of CYCLIN E.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Mutations of the BRAF gene in benign and malignant melanocytic lesions

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Molecular dissection of formation of senescence-associated heterochromatin foci

1 reference

https://api.crossref.org/works/10.1111%2FPCMR.12248

21 January 2018

Identifiers

10.1111/PCMR.12248

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

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