(Q39008798)

8 September 2017

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title

Th9 cells in the pathogenesis of EAE and multiple sclerosis (English)

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8 September 2017

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Wassim Elyaman

1

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8 September 2017

Samia J Khoury

series ordinal

2

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8 September 2017

language of work or name

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14 November 2016

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Seminars in Immunopathology

8 September 2017

published in

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8 September 2017

volume

39

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8 September 2017

issue

1

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8 September 2017

page(s)

79-87

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IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Using EAE to better understand principles of immune function and autoimmune pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Characteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 as a mediator of Th17-driven inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

The B7/CD28 costimulatory family in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

The nervous system and innate immunity: the neuropeptide connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Notch signaling regulates antigen sensitivity of naive CD4+ T cells by tuning co-stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

The different faces of Notch in T-helper-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

OX40 signaling favors the induction of T(H)9 cells and airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

CD28-independent induction of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Heteromerization of the c Chain with the Interleukin-9 Receptor Subunit Leads to STAT Activation and Prevention of Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9, a local growth factor for synovial T cells in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Induction and molecular signature of pathogenic TH17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IFN-γ limits Th9-mediated autoimmune inflammation through dendritic cell modulation of IL-27

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

BCL6 controls Th9 cell development by repressing Il9 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Opposing actions of IL-2 and IL-21 on Th9 differentiation correlate with their differential regulation of BCL6 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9-induced expansion of B-1b cells restores numbers but not function of B-1 lymphocytes in xid mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 is a Th17-derived cytokine that limits pathogenic activity in organ-specific autoimmune disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Airway allergen exposure stimulates bone marrow eosinophilia partly via IL-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 and its receptor: from signal transduction to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Mast cells are essential intermediaries in regulatory T-cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 production by regulatory T cells recruits mast cells that are essential for regulatory T cell-induced immune suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Human TH9 cells are skin-tropic and have autocrine and paracrine proinflammatory capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

B-cell depletion with rituximab in relapsing-remitting multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Neutralization of interleukin-9 ameliorates symptoms of experimental autoimmune myasthenia gravis in rats by decreasing effector T cells and altering humoral responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Progress in understanding the safety and efficacy of Janus kinase inhibitors for treatment of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 contributes to immunosuppression mediated by regulatory T cells and mast cells in B-cell non-hodgkin's lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 signaling affects central nervous system resident cells during inflammatory stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Signaling of interleukin-17 family cytokines in immunity and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 promotes Th17 cell migration into the central nervous system via CC chemokine ligand-20 produced by astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9/IL-9 receptor signaling selectively protects cortical neurons against developmental apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Neutralization of IL-9 ameliorates experimental autoimmune encephalomyelitis by decreasing the effector T cell population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

IL-9 is important for T-cell activation and differentiation in autoimmune inflammation of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

T helper 9 cells induced by plasmacytoid dendritic cells regulate interleukin-17 in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-016-0604-Y

Interleukin-9 receptor alpha chain mRNA formation in CD8+ T cells producing anti-human immunodeficiency virus type 1 substance(s).

21 January 2018

1 reference

12 December 2020

Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses

1 reference

12 December 2020

A neuropathological analysis of experimental autoimmune encephalomyelitis with predominant brain stem and cerebellar involvement and differences between active and passive induction

1 reference

12 December 2020

Interleukin-9 potentiates the interleukin-4-induced IgE and IgG1 release from murine B lymphocytes

1 reference

12 December 2020

Review of the novelties presented at the 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) (III).

1 reference

12 December 2020

IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma

1 reference

12 December 2020

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

1 reference

12 December 2020

Multiple Sclerosis: Distribution of T Cell Subsets Within Active Chronic Lesions

1 reference

12 December 2020

Therapeutic decisions in multiple sclerosis: moving beyond efficacy

1 reference

12 December 2020

1 reference

12 December 2020

Interactions between TLR7 and TLR9 agonists and receptors regulate innate immune responses by astrocytes and microglia

1 reference

12 December 2020

Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Blocking OX-40/OX-40 ligand interaction in vitro and in vivo leads to decreased T cell function and amelioration of experimental allergic encephalomyelitis.

1 reference

12 December 2020

Rescue of human T cells by interleukin-9 (IL-9) from IL-2 deprivation-induced apoptosis: correlation with alpha subunit expression of the IL-9 receptor

1 reference

12 December 2020

IL-9 and its receptor in allergic and nonallergic lung disease: increased expression in asthma

1 reference

12 December 2020

Upregulation of IL-17, but not of IL-9, in circulating cells of CIS and relapsing MS patients. Impact of corticosteroid therapy on the cytokine network

1 reference

12 December 2020

Functional and biochemical characterization of mouse P40/IL-9 receptors.

1 reference

12 December 2020

Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and prevention of apoptosis

1 reference

12 December 2020

Current status of the immunomodulation and immunomediated therapeutic strategies for multiple sclerosis

1 reference

12 December 2020

10.1007/S00281-016-0604-Y

Identifiers

DOI

1 reference

8 September 2017

1 reference