(Q39010249)

English

A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival.

scientific article published on 31 March 2014

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681948%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681948%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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inferred from title

acute myeloid leukemia

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based on heuristic

inferred from title

3

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12 March 2020

Tim C P Somervaille

7

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12 March 2020

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Julian G Jude

1

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12 March 2020

Gary J Spencer

2

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12 March 2020

Tim D D Somerville

4

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12 March 2020

David R Jones

5

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12 March 2020

Nullin Divecha

6

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12 March 2020

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publication date

31 March 2014

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12 March 2020

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Europe PubMed Central

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12 March 2020

34

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12 March 2020

10

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12 March 2020

1253-1262

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12 March 2020

Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors

1 reference

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1 reference

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Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression

1 reference

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1 reference

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9 September 2017

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1 reference

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9 September 2017

Class I phosphoinositide 3-kinases in normal and pathologic hematopoietic cells

1 reference

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9 September 2017

The PI3K/PKB signaling module as key regulator of hematopoiesis: implications for therapeutic strategies in leukemia.

1 reference

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9 September 2017

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias

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9 September 2017

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9 September 2017

Phosphatidylinositol 5-phosphate links dehydration stress to the activity of ARABIDOPSIS TRITHORAX-LIKE factor ATX1.

1 reference

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9 September 2017

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

1 reference

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9 September 2017

Phosphoinositide signalling in cancer: beyond PI3K and PTEN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130659

9 September 2017

A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5P and other phosphoinositides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130659

9 September 2017

Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.

1 reference

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9 September 2017

PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions

1 reference

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9 September 2017

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells

1 reference

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9 September 2017

Membrane recognition by phospholipid-binding domains

1 reference

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Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles

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9 September 2017

Phosphoinositides in cell regulation and membrane dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130659

9 September 2017

Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130659

9 September 2017

Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.

1 reference

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

1 reference

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Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

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Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias

1 reference

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Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress

1 reference

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PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

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10.1038/ONC.2014.77

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681948%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681948%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

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Europe PubMed Central

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12 March 2020

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