(Q39016642)

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Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2.

scientific article published on 24 February 2014

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2. (English)

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

1 reference

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prostate cancer

1 reference

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2

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Gagan Deep

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

9

object named as

Rajesh Agarwal

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

author name string

Harold J Ting

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Anil K Jain

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Adela Cimic

4

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Joseph Sirintrapun

5

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Lina M Romero

6

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Scott D Cramer

7

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Chapla Agarwal

8

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

publication date

24 February 2014

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Molecular Carcinogenesis

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

54

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

9

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

730-741

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy

1 reference

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9 September 2017

Cancer statistics, 2013

1 reference

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9 September 2017

Cancer statistics, 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

9 September 2017

Prostate cancer and inflammation: the evidence

1 reference

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9 September 2017

TGF-β signal transduction spreading to a wider field: a broad variety of mechanisms for context-dependent effects of TGF-β.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

9 September 2017

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions.

1 reference

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The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer

1 reference

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9 September 2017

Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model

1 reference

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Cancer-related inflammation

1 reference

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1 reference

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Tumor stroma and regulation of cancer development

1 reference

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1 reference

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9 September 2017

Inflammation in prostate carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

9 September 2017

Tumor microenvironment: the role of the tumor stroma in cancer

1 reference

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Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine

1 reference

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9 September 2017

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

1 reference

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The global health burden of infection-associated cancers in the year 2002

1 reference

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9 September 2017

Tumor-stroma interactions

1 reference

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9 September 2017

A system for studying epithelial-stromal interactions reveals distinct inductive abilities of stromal cells from benign prostatic hyperplasia and prostate cancer

1 reference

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1 reference

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Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation

1 reference

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9 September 2017

The role of gene-environment interaction in the aetiology of human cancer: examples from cancers of the large bowel, lung and breast.

1 reference

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1 reference

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Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland

1 reference

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Significance of multiple mutations in cancer

1 reference

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9 September 2017

Urinary and sexual function after radical prostatectomy for clinically localized prostate cancer: the Prostate Cancer Outcomes Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

9 September 2017

Fibroblasts, myofibroblasts, and wound contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

9 September 2017

Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

9 September 2017

Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

14 September 2017

Silibinin reverses epithelial-to-mesenchymal transition in metastatic prostate cancer cells by targeting transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

14 September 2017

Silibinin impairs constitutively active TGFalpha-EGFR autocrine loop in advanced human prostate carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

14 September 2017

Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

14 September 2017

Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

25 September 2017

Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

1 reference

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25 September 2017

Silibinin inhibits myofibroblast transdifferentiation in human tenon fibroblasts and reduces fibrosis in a rabbit trabeculectomy model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

21 August 2018

Individualizing quality-of-life outcomes reporting: how localized prostate cancer treatments affect patients with different levels of baseline urinary, bowel, and sexual function

1 reference

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21 August 2018

Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

21 August 2018

Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft

1 reference

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Expression analysis of peptide growth factors VEGF, FGF2, TGFB1, EGF and IGF1 in prostate cancer and benign prostatic hyperplasia.

1 reference

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21 August 2018

Meat consumption among Black and White men and risk of prostate cancer in the Cancer Prevention Study II Nutrition Cohort.

1 reference

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21 August 2018

A gain of function TGFB1 polymorphism may be associated with late stage prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

21 August 2018

Suppression of advanced human prostate tumor growth in athymic mice by silibinin feeding is associated with reduced cell proliferation, increased apoptosis, and inhibition of angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

21 August 2018

Silibinin inhibits constitutive and TNFalpha-induced activation of NF-kappaB and sensitizes human prostate carcinoma DU145 cells to TNFalpha-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

21 August 2018

A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4208986

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TGFB1 polymorphisms are associated with risk of late normal tissue complications in the breast after radiotherapy for early breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FMC.22135

21 January 2018

Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated

1 reference

https://pubmed.ncbi.nlm.nih.gov/24615813

12 December 2020

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10.1002/MC.22135

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24 November 2022

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PMC publication ID

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PubMed publication ID

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