(Q39019412)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28089889%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

title

MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28089889%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference

22

1 reference

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9 April 2020

Ismail Can

5

1 reference

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9 April 2020

Jason Gertz

24

1 reference

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9 April 2020

Jane E Johnson

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28089889%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Trudy G Oliver

29

1 reference

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9 April 2020

17

Timothy L Mosbruger

1 reference

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9 April 2020

Robert J Wechsler-Reya

27

object named as

Robert J Wechsler-Reya

1 reference

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9 April 2020

author name string

Gurkan Mollaoglu

1

1 reference

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9 April 2020

Matthew R Guthrie

2

1 reference

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9 April 2020

Stefanie Böhm

3

1 reference

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9 April 2020

Johannes Brägelmann

4

1 reference

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9 April 2020

Paul M Ballieu

6

1 reference

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9 April 2020

Annika Marx

7

1 reference

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9 April 2020

Julie George

8

1 reference

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9 April 2020

Christine Heinen

9

1 reference

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9 April 2020

Milind D Chalishazar

10

1 reference

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9 April 2020

Haixia Cheng

11

1 reference

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9 April 2020

Abbie S Ireland

12

1 reference

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9 April 2020

Kendall E Denning

13

1 reference

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9 April 2020

Anandaroop Mukhopadhyay

14

1 reference

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9 April 2020

Jeffery M Vahrenkamp

15

1 reference

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9 April 2020

Kristofer C Berrett

16

1 reference

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9 April 2020

Jun Wang

18

1 reference

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9 April 2020

Jessica L Kohan

19

1 reference

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9 April 2020

Mohamed E Salama

20

1 reference

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9 April 2020

Benjamin L Witt

21

1 reference

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9 April 2020

Roman K Thomas

23

1 reference

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9 April 2020

Adi F Gazdar

26

1 reference

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9 April 2020

Martin L Sos

28

1 reference

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9 April 2020

language of work or name

1 reference

12 January 2017

1 reference

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9 April 2020

1 reference

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9 April 2020

volume

31

1 reference

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9 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28089889%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

page(s)

270-285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28089889%20AND%20SRC:MED&resulttype=core&format=json

ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs

9 April 2020

cites work

1 reference

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Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility

17 June 2018

1 reference

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Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression.

17 June 2018

1 reference

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Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo

17 June 2018

1 reference

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Origins, genetic landscape, and emerging therapies of small cell lung cancer

17 June 2018

1 reference

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Comprehensive genomic profiles of small cell lung cancer

17 June 2018

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Small cell lung cancer: will recent progress lead to improved outcomes?

17 June 2018

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DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2.

17 June 2018

1 reference

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Safety and activity of alisertib, an investigational aurora kinase A inhibitor, in patients with breast cancer, small-cell lung cancer, non-small-cell lung cancer, head and neck squamous-cell carcinoma, and gastro-oesophageal adenocarcinoma: a five-

17 June 2018

1 reference

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The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung

17 June 2018

1 reference

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Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Drugging MYCN through an allosteric transition in Aurora kinase A

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Sox2 cooperates with Lkb1 loss in a mouse model of squamous cell lung cancer

17 June 2018

1 reference

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Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing

17 June 2018

1 reference

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PTEN is a potent suppressor of small cell lung cancer.

17 June 2018

1 reference

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Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells

17 June 2018

1 reference

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Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Selective tropism of Seneca Valley virus for variant subtype small cell lung cancer.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.

17 June 2018

1 reference

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A framework for identification of actionable cancer genome dependencies in small cell lung cancer

17 June 2018

1 reference

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

17 June 2018

1 reference

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Functional genomics identifies therapeutic targets for MYC-driven cancer

17 June 2018

1 reference

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An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735.

17 June 2018

1 reference

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Update on small cell carcinoma and its differentiation from squamous cell carcinoma and other non-small cell carcinomas

17 June 2018

1 reference

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Nuclear factor I/B is an oncogene in small cell lung cancer

17 June 2018

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A functional role for tumor cell heterogeneity in a mouse model of small cell lung cancer

17 June 2018

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Neuroendocrine tumors of the lung: an update

17 June 2018

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Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase

17 June 2018

1 reference

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Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma

17 June 2018

1 reference

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Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

17 June 2018

1 reference

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Lung tumours with neuroendocrine differentiation

17 June 2018

1 reference

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Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma

17 June 2018

1 reference

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AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis

17 June 2018

1 reference

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Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Characterization of variant subclasses of cell lines derived from small cell lung cancer having distinctive biochemical, morphological, and growth properties

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Establishment and identification of small cell lung cancer cell lines having classic and variant features.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

myc family DNA amplification in 107 tumors and tumor cell lines from patients with small cell lung cancer treated with different combination chemotherapy regimens

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

myc family DNA amplification in tumors and tumor cell lines from patients with small-cell lung cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Efficacy and safety of biweekly i.v. administrations of the Aurora kinase inhibitor danusertib hydrochloride in independent cohorts of patients with advanced or metastatic breast, ovarian, colorectal, pancreatic, small-cell and non-small-cell lung c

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5310991

Metastatic patterns in small-cell lung cancer: correlation of autopsy findings with clinical parameters in 537 patients

21 August 2018

1 reference

12 December 2020

Small cell lung cancer

1 reference

12 December 2020

Activation of myc gene family in human lung carcinomas and during heterotransplantation into nude mice

1 reference

12 December 2020

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

1 reference

12 December 2020

10.1016/J.CCELL.2016.12.005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28089889%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28089889%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

PubMed publication ID

28089889

1 reference