(Q39027758)

8 September 2017

Lipid nanoparticle delivery systems for siRNA-based therapeutics (English)

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8 September 2017

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C Wan

1

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PubMed ID

25786618

8 September 2017

T M Allen

series ordinal

2

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PubMed ID

25786618

8 September 2017

P R Cullis

series ordinal

3

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8 September 2017

1 February 2014

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Drug delivery and translational research

8 September 2017

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8 September 2017

4

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8 September 2017

1

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8 September 2017

74-83

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https://scigraph.springernature.com/pub.10.1007/s13346-013-0161-z

8 September 2017

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cites work

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

siRNAs: potential therapeutic agents against hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

RNAi for treating hepatitis B viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

RNA interference-based therapeutics for human immunodeficiency virus HIV-1 treatment: synthetic siRNA or vector-based shRNA?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

siRNA-based approaches in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Therapeutic potential of RNA interference against cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

RNAi silencing in mouse models of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

RNA interference for CFTR attenuates lung fluid absorption at birth in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Chemical modification of siRNAs for in vivo use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

The silent treatment: siRNAs as small molecule drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Action and reaction: the biological response to siRNA and its delivery vehicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

siRNA function in RNAi: a chemical modification analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Membrane models with phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

From "banghasomes" to liposomes: a memoir of Alec Bangham, 1921-2010.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Drug entrapment in liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

The carrier potential of liposomes in biology and medicine (second of two parts)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Liposomes as carriers of enzymes or drugs: a new approach to the treatment of storage diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

21 January 2018

Liposomal nanomedicines

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

21 January 2018

12 December 2020

Vesicles of variable sizes produced by a rapid extrusion procedure

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Single bilayer liposomes prepared without sonication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Chaotic mixer for microchannels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Entrapment of small molecules and nucleic acid-based drugs in liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Openings between defective endothelial cells explain tumor vessel leakiness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Transport of molecules across tumor vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Physiologic upper limits of pore size of different blood capillary types and another perspective on the dual pore theory of microvascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

The effect of particle size and charge on the clearance rates of liposomes and liposome encapsulated drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Effect of fetal calf serum and serum protein fractions on the uptake of liposomal phosphatidylcholine by rat hepatocytes in primary monolayer culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Differential properties of organ-specific serum opsonins for liver and spleen macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Therapy of primary and metastatic mouse mammary carcinomas with doxorubicin encapsulated in long circulating liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Liposomal doxorubicin (Doxil): an effective new treatment for Kaposi's sarcoma in AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Efficacy and safety of pegylated liposomal Doxorubicin in combination with bortezomib for multiple myeloma: effects of adverse prognostic factors on outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Liposomal drug delivery systems: from concept to clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Cationic liposome-mediated transfection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Cationic lipid vectors for plasmid DNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

The design of cationic lipids for gene delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Comparison of cell proliferation and toxicity assays using two cationic liposomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Toxicity and immunomodulatory activity of liposomal vectors formulated with cationic lipids toward immune effector cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Spontaneous entrapment of polynucleotides upon electrostatic interaction with ethanol-destabilized cationic liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Roles of lipid polymorphism in intracellular delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Rational design of cationic lipids for siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Stabilized plasmid-lipid particles: a systemic gene therapy vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Stabilized plasmid-lipid particles: construction and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Influence of cationic lipid composition on gene silencing properties of lipid nanoparticle formulations of siRNA in antigen-presenting cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

VEGFA and tumour angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

In vivo quantification of formulated and chemically modified small interfering RNA by heating-in-Triton quantitative reverse transcription polymerase chain reaction (HIT qRT-PCR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Familial amyloidotic polyneuropathy and transthyretin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Strategies for proprotein convertase subtilisin kexin 9 modulation: a perspective on recent patents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Clinical aspects of PCSK9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

The role of proprotein convertase subtilisin/kexin type 9 in hyperlipidemia: focus on therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13346-013-0161-Z

Preparation of unilamellar liposomes of intermediate size (0.1–0.2 μm) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes

21 January 2018

1 reference

12 December 2020

Stabilized plasmid-lipid particles containing PEG-diacylglycerols exhibit extended circulation lifetimes and tumor selective gene expression

1 reference

12 December 2020

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

1 reference

12 December 2020

Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient

1 reference

12 December 2020

Enhanced localization of liposomes with prolonged blood circulation time in infected lung tissue

1 reference

12 December 2020

Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients

1 reference

12 December 2020

Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes

1 reference

12 December 2020

The carrier potential of liposomes in biology and medicine (first of two parts)

1 reference

12 December 2020

Liposomal vincristine which exhibits increased drug retention and increased circulation longevity cures mice bearing P388 tumors

1 reference

12 December 2020

Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice

1 reference

12 December 2020

The effect of entrapment in liposomes on the in vivo distribution of [3H]methotrexate in a primate

1 reference

12 December 2020

RNA interference-based gene therapy for successful treatment of rheumatoid arthritis

1 reference

12 December 2020

Preclinical pharmacology, toxicology and efficacy of sphingomyelin/cholesterol liposomal vincristine for therapeutic treatment of cancer

1 reference

12 December 2020

Pharmacokinetics of stealth versus conventional liposomes: effect of dose

1 reference

12 December 2020

Studies on phosphatidylcholine vesicles. Formation and physical characteristics

1 reference

12 December 2020

Stealth liposomes: an improved sustained release system for 1-beta-D-arabinofuranosylcytosine

1 reference

12 December 2020

Optimization of the retention properties of vincristine in liposomal systems

1 reference

12 December 2020

Differential scanning calorimetry and 31P NMR studies on sonicated and unsonicated phosphatidylcholine liposomes

1 reference

12 December 2020

Pharmacokinetics and antitumor activity of epirubicin encapsulated in long-circulating liposomes incorporating a polyethylene glycol-derivatized phospholipid

1 reference

12 December 2020

Control of the rate of hepatic uptake and catabolism of liposome-entrapped proteins injected into rats. Possible therapeutic applications

1 reference

12 December 2020

Accelerated clearance of PEGylated liposomes in rats after repeated injections

1 reference

12 December 2020

Silencing of polo-like kinase (Plk) 1 via siRNA causes induction of apoptosis and impairment of mitosis machinery in human prostate cancer cells: implications for the treatment of prostate cancer.

1 reference

12 December 2020

Fusion of dipalmitoylphosphatidylcholine vesicles

1 reference

12 December 2020

Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells

1 reference

12 December 2020

Diffusion of univalent ions across the lamellae of swollen phospholipids

1 reference

12 December 2020

Outside-inside distributions and sizes of mixed phosphatidylcholine-cholesterol vesicles

1 reference

12 December 2020

Clinical efficacy and prospects for use of pegylated liposomal doxorubicin in the treatment of ovarian and breast cancers

1 reference

12 December 2020

RNA interference trigger variants: getting the most out of RNA for RNA interference-based therapeutics

1 reference

12 December 2020

10.1007/S13346-013-0161-Z

Identifiers

DOI

1 reference

8 September 2017

1 reference

PubMed ID

25786618