(Q39032609)

8 September 2017

Parasite excretory-secretory products and their effects on metabolic syndrome (English)

1 reference

8 September 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28066896%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

William Harnett

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28066896%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

F E Lumb

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28066896%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

M M Harnett

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28066896%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

9 January 2017

1 reference

8 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28066896%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28066896%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28066896%20AND%20SRC:MED&resulttype=core&format=json

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

9 June 2020

cites work

1 reference

Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis

21 January 2018

1 reference

Cellular survival: a play in three Akts

21 January 2018

1 reference

Intracellular signaling by Akt: bound to be specific

21 January 2018

1 reference

IGF-I receptor signalling in transformation and differentiation

21 January 2018

1 reference

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

21 January 2018

1 reference

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

Akt, FoxO and regulation of apoptosis

21 January 2018

1 reference

Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.

21 January 2018

1 reference

Linking calorie restriction to longevity through sirtuins and autophagy: any role for TOR.

21 January 2018

1 reference

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

21 January 2018

1 reference

Inflammatory mechanisms in obesity

21 January 2018

1 reference

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

21 January 2018

1 reference

TLR4 links innate immunity and fatty acid-induced insulin resistance

21 January 2018

1 reference

MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity

21 January 2018

1 reference

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

21 January 2018

1 reference

Tumor necrosis factor-α signaling in macrophages.

21 January 2018

1 reference

Novel, non-antigen-specific therapeutic approaches to autoimmune/inflammatory diseases

21 January 2018

1 reference

The NLRP3 inflammasome: a sensor for metabolic danger?

21 January 2018

1 reference

Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes.

21 January 2018

1 reference

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

21 January 2018

1 reference

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

21 January 2018

1 reference

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

21 January 2018

1 reference

NLRP3 at the interface of metabolism and inflammation.

21 January 2018

1 reference

T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.

21 January 2018

1 reference

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

21 January 2018

1 reference

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

21 January 2018

1 reference

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

21 January 2018

1 reference

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 January 2018

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Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

1 reference

Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages

21 January 2018

1 reference

Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis

21 January 2018

1 reference

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

21 January 2018

1 reference

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

21 January 2018

1 reference

Adipose-Resident Group 1 Innate Lymphoid Cells Promote Obesity-Associated Insulin Resistance

21 January 2018

1 reference

Normalization of obesity-associated insulin resistance through immunotherapy

21 January 2018

1 reference

T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice

21 January 2018

1 reference

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

21 January 2018

1 reference

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

21 January 2018

1 reference

Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation.

21 January 2018

1 reference

Immune regulation by helminth parasites: cellular and molecular mechanisms

21 January 2018

1 reference

Helminth immunoregulation: the role of parasite secreted proteins in modulating host immunity.

21 January 2018

1 reference

Secretory products of helminth parasites as immunomodulators.

21 January 2018

1 reference

Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications

21 January 2018

1 reference

Helminth-derived immunomodulators: can understanding the worm produce the pill?

21 January 2018

1 reference

Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway

21 January 2018

1 reference

Leishmania mexicana promastigotes inhibit macrophage IL-12 production via TLR-4 dependent COX-2, iNOS and arginase-1 expression

21 January 2018

1 reference

Impact of Leishmania mexicana infection on dendritic cell signaling and functions

21 January 2018

1 reference

Susceptibility to Leishmania mexicana infection is due to the inability to produce IL-12 rather than lack of IL-12 responsiveness.

21 January 2018

1 reference

The Leishmania mexicana cysteine protease, CPB2.8, induces potent Th2 responses

21 January 2018

1 reference

Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Helminth infection in populations undergoing epidemiological transition: a friend or foe?

21 January 2018

1 reference

Decreased prevalence of lymphatic filariasis among subjects with type-1 diabetes

21 January 2018

1 reference

Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity

21 January 2018

1 reference

Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice

21 January 2018

1 reference

Filarial Infection or Antigen Administration Improves Glucose Tolerance in Diet-Induced Obese Mice.

21 January 2018

1 reference

An anti-atherogenic effect of Schistosoma mansoni infections in mice associated with a parasite-induced lowering of blood total cholesterol

21 January 2018

1 reference

Effects of Schistosoma mansoni worms and eggs on circulating cholesterol and liver lipids in mice.

21 January 2018

1 reference

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

21 January 2018

1 reference

Microfilariae of Brugia malayi Inhibit the mTOR Pathway and Induce Autophagy in Human Dendritic Cells

21 January 2018

1 reference

Impact of Leishmania metalloprotease GP63 on macrophage signaling

21 January 2018

1 reference

Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection

21 January 2018

1 reference

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

21 January 2018

1 reference

Leishmania donovani-induced ceramide as the key mediator of Akt dephosphorylation in murine macrophages: role of protein kinase Czeta and phosphatase

21 January 2018

1 reference

Macrophage mTORC1 disruption reduces inflammation and insulin resistance in obese mice.

21 January 2018

1 reference

Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice

21 January 2018

1 reference

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

1 reference

Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells.

21 January 2018

1 reference

The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis

21 January 2018

1 reference

ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteae.

21 January 2018

1 reference

Dendritic cell activation and function in response to Schistosoma mansoni.

21 January 2018

1 reference

Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways

21 January 2018

1 reference

Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses.

21 January 2018

1 reference

Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions.

21 January 2018

1 reference

Inflammation in atherosclerosis

21 January 2018

1 reference

Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis

21 January 2018

1 reference

Metabolic syndrome: the danger signal in atherosclerosis

21 January 2018

1 reference

A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62.

21 January 2018

1 reference

The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice

21 January 2018

1 reference

Impaired clearance of apoptotic cells promotes synergy between atherogenesis and autoimmune disease

21 January 2018

1 reference

The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model

21 January 2018

1 reference

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue

21 January 2018

1 reference

Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control

21 January 2018

1 reference

Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.

21 January 2018

1 reference

Molecular cloning and characterization of peroxiredoxin from Toxoplasma gondii

21 January 2018

1 reference

Toxoplasma gondii peroxiredoxin promotes altered macrophage function, caspase-1-dependent IL-1β secretion enhances parasite replication

21 January 2018

1 reference

Alternative activation of ruminant macrophages by Fasciola hepatica

21 January 2018

1 reference

Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages.

21 January 2018

1 reference

The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation.

21 January 2018

1 reference

Phosphocholine-containing ligands direct CRP induction of M2 macrophage polarization independent of T cell polarization: Implication for chronic inflammatory states

21 January 2018

1 reference

A parasitic helminth-derived peptide that targets the macrophage lysosome is a novel therapeutic option for autoimmune disease.

21 January 2018

1 reference

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome

21 January 2018

1 reference

PKC/ROS-Mediated NLRP3 Inflammasome Activation Is Attenuated by Leishmania Zinc-Metalloprotease during Infection

21 January 2018

1 reference

Innate sensors of pathogen and stress: linking inflammation to obesity

21 January 2018

1 reference

The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype

21 January 2018

1 reference

The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma

21 January 2018

1 reference

Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation.

21 January 2018

1 reference

Modulation of host immune responses by helminth glycans

21 January 2018

1 reference

Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation

21 January 2018

1 reference

Soluble egg antigen from Schistosoma japonicum modulates the progression of chronic progressive experimental autoimmune encephalomyelitis via Th2-shift response.

21 January 2018

1 reference

Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes

21 January 2018

1 reference

Maturation of dendritic cell 2 phenotype by a helminth glycan uses a Toll-like receptor 4-dependent mechanism

21 January 2018

1 reference

Thioredoxin peroxidase secreted by Fasciola hepatica induces the alternative activation of macrophages

21 January 2018

1 reference

Secreted proteins from the helminth Fasciola hepatica inhibit the initiation of autoreactive T cell responses and prevent diabetes in the NOD mouse

21 January 2018

1 reference

Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses

21 January 2018

1 reference

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.

21 January 2018

1 reference

Experimental autoimmune encephalomyelitis can be prevented and cured by infection with Trypanosoma cruzi

21 January 2018

1 reference

Selective maturation of dendritic cells byNippostrongylus brasiliensis-secreted proteins drives Th2 immune responses

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/PIM.12410

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28066896%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference