(Q39042970)

English

Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells

scientific article published on 16 December 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

1 reference

based on heuristic

inferred from title

Platycodon grandiflorum

object named as

Platycodon grandiflorum

1 reference

based on heuristic

inferred from title

author name string

Jae Ho Choi

1

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Europe PubMed Central

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8 September 2017

Yong Pil Hwang

2

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8 September 2017

Hyung Gyun Kim

3

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Europe PubMed Central

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8 September 2017

Tilak Khanal

4

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Europe PubMed Central

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8 September 2017

Minh Truong Do

5

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8 September 2017

Sun Woo Jin

6

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8 September 2017

Hwa Jeong Han

7

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8 September 2017

Hyun Sun Lee

8

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Europe PubMed Central

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8 September 2017

Young Chun Lee

9

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8 September 2017

Young Chul Chung

10

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8 September 2017

Tae Cheon Jeong

11

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8 September 2017

Hye Gwang Jeong

12

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8 September 2017

language of work or name

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publication date

16 December 2013

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8 September 2017

Nutrition and Cancer

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8 September 2017

66

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8 September 2017

1

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8 September 2017

140-151

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8 September 2017

An overview of epithelio-mesenchymal transformation

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

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Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

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Saponins derived from the roots of Platycodon grandiflorum inhibit HT-1080 cell invasion and MMPs activities: regulation of NF-kappaB activation via ROS signal pathway

1 reference

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21 January 2018

Protective effect of saponins derived from the roots of Platycodon grandiflorum against carbon tetrachloride induced hepatotoxicity in mice.

1 reference

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21 January 2018

Saponins isolated from the root of Platycodon grandiflorum protect against acute ethanol-induced hepatotoxicity in mice.

1 reference

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21 January 2018

Protective effects of saponins from the root of Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the activation of AMP-dependent protein kinase.

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21 January 2018

Inhibition of acrolein-stimulated MUC5AC expression by Platycodon grandiflorum root-derived saponin in A549 cells.

1 reference

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21 January 2018

Protective effect of Platycodi radix on carbon tetrachloride-induced hepatotoxicity

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21 January 2018

Hepatoprotective effects of Platycodon grandiflorum on acetaminophen-induced liver damage in mice

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21 January 2018

Suppressive effects of Platycodon grandiflorum on the progress of carbon tetrachloride-induced hepatic fibrosis.

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21 January 2018

Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation

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Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

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GSK3, a master switch regulating cell-fate specification and tumorigenesis

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Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition

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21 January 2018

Tetraspanin CD151 regulates transforming growth factor beta signaling: implication in tumor metastasis.

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21 January 2018

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling

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Emergence of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin axis in transforming growth factor-β-induced epithelial-mesenchymal transition

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TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease

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Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition

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Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways

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TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts.

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Inhibition of PI3K prevents the proliferation and differentiation of human lung fibroblasts into myofibroblasts: the role of class I P110 isoforms

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Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro

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Studies on the saponins of the root of Platycodon grandiflorum A. De Candolle. I. Isolation and the structure of platycodin-D

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/CPB.23.2965

Identifiers

10.1080/01635581.2014.853087

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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