(Q39064812)

English

Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease

scientific article published on 9 November 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

author name string

Bong-Suk Choi

1

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Hyool Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Hyo Jeong Lee

3

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Kumar Sapkota

4

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Se Eun Park

5

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Seung Kim

6

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Sung-Jun Kim

7

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

publication date

9 November 2013

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Europe PubMed Central

PubMed publication ID

8 September 2017

Neurochemical Research

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Europe PubMed Central

PubMed publication ID

8 September 2017

39

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Europe PubMed Central

PubMed publication ID

8 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

84-96

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

https://scigraph.springernature.com/pub.10.1007/s11064-013-1193-y

0 references

Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Celastrol: Molecular targets of Thunder God Vine

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Celastrol: a new therapeutic potential of traditional Chinese medicine

1 reference

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21 January 2018

The triterpene celastrol as a very potent inhibitor of lipid peroxidation in mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer.

1 reference

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21 January 2018

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Suppression of inflammatory responses by celastrol, a quinone methide triterpenoid isolated from Celastrus regelii

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease

1 reference

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21 January 2018

Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.

1 reference

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21 January 2018

Induction of heat shock proteins in differentiated human and rodent neurons by celastrol

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Oxidative stress in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Complex I and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Disease modification in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

The rotenone model of Parkinson's disease: genes, environment and mitochondria

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

A highly reproducible rotenone model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Celastrol protects human neuroblastoma SH-SY5Y cells from rotenone-induced injury through induction of autophagy

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Multi-target-directed ligands to combat neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Carnosol, a component of rosemary (Rosmarinus officinalis L.) protects nigral dopaminergic neuronal cells

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Detoxified extract of Rhus verniciflua stokes inhibits rotenone-induced apoptosis in human dopaminergic cells, SH-SY5Y.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Oxidative stress and the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Science, medicine, and the future: Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Mitochondrial biology and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Targeting programmed cell death in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Pathological roles of MAPK signaling pathways in human diseases

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Celastrol inhibits pro-inflammatory cytokine secretion in Crohn's disease biopsies.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Celastrols as inducers of the heat shock response and cytoprotection.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid

1 reference

https://api.crossref.org/works/10.1007%2FS11064-013-1193-Y

21 January 2018

Teaching old drugs new tricks. Meeting of the Neurodegeneration Drug Screening Consortium, 7-8 April 2002, Washington, DC, USA

1 reference

https://pubmed.ncbi.nlm.nih.gov/24214023

12 December 2020

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Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24214023

12 December 2020

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Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24214023

12 December 2020

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Mechanism of toxicity in rotenone models of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24214023

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Neurologists strike gold in drug screen effort

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Identifiers

10.1007/S11064-013-1193-Y

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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