(Q39065652)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26984067%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

title

Functionally different α-synuclein inclusions yield insight into Parkinson's disease pathology (English)

1 reference

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11 March 2020

0 references

1 reference

1 reference

2

1 reference

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11 March 2020

Arshdeep Sidhu

6

1 reference

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11 March 2020

author name string

Christian C Raiss

1

1 reference

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11 March 2020

Irene B M Konings

3

1 reference

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11 March 2020

Heinrich Grabmayr

4

1 reference

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11 March 2020

Gerco C Hassink

5

1 reference

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11 March 2020

Joost le Feber

7

1 reference

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11 March 2020

Andreas R Bausch

8

1 reference

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11 March 2020

Casper Jansen

9

1 reference

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11 March 2020

Vinod Subramaniam

10

1 reference

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11 March 2020

Mireille M A E Claessens

11

1 reference

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11 March 2020

language of work or name

English

0 references

publication date

17 March 2016

1 reference

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11 March 2020

1 reference

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11 March 2020

volume

6

1 reference

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11 March 2020

page(s)

23116

1 reference

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Creative Commons Attribution 4.0 International

11 March 2020

copyright license

start time

17 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/srep23116

0 references

cites work

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Sorting out the trash: the spatial nature of eukaryotic protein quality control

9 September 2017

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9 September 2017

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Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells

9 September 2017

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The role of alpha-synuclein oligomerization and aggregation in cellular and animal models of Parkinson's disease

9 September 2017

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Molecular mechanisms of amyloid oligomers toxicity

9 September 2017

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Α-synuclein misfolding and Parkinson's disease

9 September 2017

1 reference

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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

9 September 2017

1 reference

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In vitro recapitulation of aberrant protein inclusions in neurodegenerative diseases: New cellular models of neurodegenerative diseases.

9 September 2017

1 reference

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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

9 September 2017

1 reference

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Polyglutamine shows a urea-like affinity for unfolded cytosolic protein

9 September 2017

1 reference

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Cellular strategies for controlling protein aggregation

9 September 2017

1 reference

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Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity

9 September 2017

1 reference

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Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

9 September 2017

1 reference

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Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

9 September 2017

1 reference

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Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

9 September 2017

1 reference

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A timeline for Parkinson's disease

9 September 2017

1 reference

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Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity

9 September 2017

1 reference

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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

9 September 2017

1 reference

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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

9 September 2017

1 reference

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Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates

9 September 2017

1 reference

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Molecular mechanisms of alpha-synuclein neurodegeneration

9 September 2017

1 reference

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Misfolded proteins partition between two distinct quality control compartments

9 September 2017

1 reference

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Structural classification of toxic amyloid oligomers

9 September 2017

1 reference

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Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

9 September 2017

1 reference

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STED microscopy with a supercontinuum laser source

9 September 2017

1 reference

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Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases

9 September 2017

1 reference

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Subdiffraction resolution in far-field fluorescence microscopy

9 September 2017

1 reference

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Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation

9 September 2017

2 references

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9 September 2017

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Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases.

2 December 2018

1 reference

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

9 September 2017

1 reference

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

9 September 2017

1 reference

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Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from alpha-synuclein mutants

9 September 2017

1 reference

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

9 September 2017

1 reference

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The neuromythology of Parkinson's Disease

9 September 2017

1 reference

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Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Staging of brain pathology related to sporadic Parkinson's disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

"Fatal attractions" of proteins. A comprehensive hypothetical mechanism underlying Alzheimer's disease and other neurodegenerative disorders.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome).

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Effects of chronic low dose rotenone treatment on human microglial cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Cytosolic catechols inhibit alpha-synuclein aggregation and facilitate the formation of intracellular soluble oligomeric intermediates.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Conformational diversity of wild-type Tau fibrils specified by templated conformation change

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Confinement to organelle-associated inclusion structures mediates asymmetric inheritance of aggregated protein in budding yeast.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Cyclosporin-A-induced prion protein aggresomes are dynamic quality-control cellular compartments

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Role of reactive oxygen species-dependent protein aggregation in metabolic stress-induced necrosis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Alpha-synuclein induces migration of BV-2 microglial cells by up-regulation of CD44 and MT1-MMP.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

The effect of learning on bursting.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Concentration dependence of alpha-synuclein fibril length assessed by quantitative atomic force microscopy and statistical-mechanical theory

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Motor score of the Unified Parkinson Disease Rating Scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Amyloid fibril formation of alpha-synuclein is accelerated by preformed amyloid seeds of other proteins: implications for the mechanism of transmissible conformational diseases

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Analysis of alpha-synuclein-associated proteins by quantitative proteomics

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Alpha-synuclein in blood and brain from familial Parkinson disease with SNCA locus triplication

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Numerous and widespread alpha-synuclein-negative Lewy bodies in an asymptomatic patient

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794800

Towards an improved serum-free, chemically defined medium for long-term culturing of cerebral cortex tissue

21 August 2018

1 reference

12 December 2020

In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies

1 reference

12 December 2020

A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease

1 reference

12 December 2020

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

1 reference

12 December 2020

A stable proportion of Lewy body bearing neurons in the substantia nigra suggests a model in which the Lewy body causes neuronal death

1 reference

12 December 2020

Assessment of α-Synuclein Pathology: A Study of the BrainNet Europe Consortium

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP23116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26984067%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26984067%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

PubMed publication ID

26984067

1 reference