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Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade
scientific article published on 6 November 2013
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scholarly article
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Europe PubMed Central
PMCID
3911663
retrieved
8 September 2017
title
Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade
(English)
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Europe PubMed Central
PMCID
3911663
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8 September 2017
main subject
Adenoviridae
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inferred from title
author
Saskia C Stein
series ordinal
2
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Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
author name string
Eric Lam
series ordinal
1
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Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
Erik Falck-Pedersen
series ordinal
3
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Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
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5 June 2020
language of work or name
English
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publication date
6 November 2013
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Europe PubMed Central
PMCID
3911663
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8 September 2017
published in
Journal of Virology
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Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
volume
88
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stated in
Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
issue
2
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stated in
Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
page(s)
974-981
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Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
cites work
Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
1 reference
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PubMed Central
reference URL
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9 September 2017
Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
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PubMed Central
reference URL
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9 September 2017
Structural mechanism of cytosolic DNA sensing by cGAS
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PubMed Central
reference URL
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9 September 2017
cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.
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PubMed Central
reference URL
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9 September 2017
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING
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PubMed Central
reference URL
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9 September 2017
Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
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PubMed Central
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Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
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9 September 2017
RNA-based mechanisms regulating host-virus interactions
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9 September 2017
DNA recognition in immunity and disease
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9 September 2017
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
5,6-Dimethylxanthenone-4-acetic acid (DMXAA) activates stimulator of interferon gene (STING)-dependent innate immune pathways and is regulated by mitochondrial membrane potential
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9 September 2017
The structural basis for the sensing and binding of cyclic di-GMP by STING
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9 September 2017
Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
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PubMed Central
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9 September 2017
RNA therapeutics: beyond RNA interference and antisense oligonucleotides
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9 September 2017
STING is a direct innate immune sensor of cyclic di-GMP
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
The PYHIN protein family as mediators of host defenses.
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9 September 2017
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
Emerging role of ISG15 in antiviral immunity
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9 September 2017
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
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PubMed Central
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9 September 2017
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity
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PubMed Central
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9 September 2017
Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases
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9 September 2017
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB
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PubMed Central
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9 September 2017
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling
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PubMed Central
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9 September 2017
Key role of splenic myeloid DCs in the IFN-alphabeta response to adenoviruses in vivo
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9 September 2017
Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors
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9 September 2017
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
Analyzing real-time PCR data by the comparative C(T) method
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9 September 2017
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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9 September 2017
Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator
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9 September 2017
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9 September 2017
Fiber and penton base capsid modifications yield diminished adenovirus type 5 transduction and proinflammatory gene expression with retention of antigen-specific humoral immunity
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IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
retrieved
21 August 2018
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1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3911663
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21 August 2018
Sensitization of IFN-γ Jak-STAT signaling during macrophage activation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24198409
retrieved
12 December 2020
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Identifiers
DOI
10.1128/JVI.02702-13
1 reference
stated in
Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
PMCID
3911663
1 reference
stated in
Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
PubMed ID
24198409
1 reference
stated in
Europe PubMed Central
PMCID
3911663
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24198409%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 June 2020
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