(Q39067597)

8 September 2017

title

Structure-based antivirals for emerging and neglected RNA viruses: an emerging field for medicinal chemistry in academia (English)

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8 September 2017

1

Rolf Hilgenfeld

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8 September 2017

publication date

1 July 2010

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Future Medicinal Chemistry

8 September 2017

published in

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8 September 2017

volume

2

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8 September 2017

issue

7

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8 September 2017

page(s)

1061-1067

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The development of antiretroviral therapy and its impact on the HIV-1/AIDS pandemic

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.211

Antiviral therapy: quo vadis?

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Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

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The 3-D structure of HIV-1 proteinase and the design of antiviral agents for the treatment of AIDS.

21 January 2018

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Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

21 January 2018

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HIVdb: a database of the structures of human immunodeficiency virus protease

21 January 2018

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Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds

21 January 2018

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Recent advances in targeting viral proteases for the discovery of novel antivirals

21 January 2018

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Selective inhibitors of picornavirus replication

21 January 2018

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Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes

21 January 2018

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Structure-based design of a parallel synthetic array directed toward the discovery of irreversible inhibitors of human rhinovirus 3C protease.

21 January 2018

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Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor.

21 January 2018

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21 January 2018

Rhinovirus chemotherapy

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Enterovirus 71 outbreak in the People's Republic of China in 2008.

21 January 2018

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An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China.

21 January 2018

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The VIZIER project: preparedness against pathogenic RNA viruses

21 January 2018

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Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein

21 January 2018

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On the size of the active site in proteases. I. Papain

21 January 2018

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Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents.

21 January 2018

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Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

21 January 2018

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Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

21 January 2018

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The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

21 January 2018

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A structural view of the inactivation of the SARS coronavirus main proteinase by benzotriazole esters

21 January 2018

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An efficient method for the synthesis of peptide aldehyde libraries employed in the discovery of reversible SARS coronavirus main protease (SARS-CoV Mpro) inhibitors

21 January 2018

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Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode

21 January 2018

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Three-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease

21 January 2018

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Design of chemical libraries with potentially bioactive molecules applying a maximum common substructure concept

21 January 2018

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A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

21 January 2018

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Ecoepidemiology and complete genome comparison of different strains of severe acute respiratory syndrome-related Rhinolophus bat coronavirus in China reveal bats as a reservoir for acute, self-limiting infection that allows recombination events

21 January 2018

1 reference

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Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans

21 January 2018

1 reference

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Distant relatives of severe acute respiratory syndrome coronavirus and close relatives of human coronavirus 229E in bats, Ghana

21 January 2018

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Identification of SARS-like coronaviruses in horseshoe bats (Rhinolophus hipposideros) in Slovenia

21 January 2018

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Detection and prevalence patterns of group I coronaviruses in bats, northern Germany

21 January 2018

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Identification of a new human coronavirus

21 January 2018

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Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia

21 January 2018

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A case for developing antiviral drugs against polio

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.211

Evidence for emergence of diverse polioviruses from C-cluster coxsackie A viruses and implications for global poliovirus eradication

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.211

Co-circulation and evolution of polioviruses and species C enteroviruses in a district of Madagascar

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.211

Potential use of antiviral agents in polio eradication

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.211

Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.211

The emerging academic drug-discovery sector

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.10.211

21 January 2018

Identifiers

DOI

10.4155/FMC.10.211

1 reference

release_jlasuix72vahrpn33hpgicllie

8 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jlasuix72vahrpn33hpgicllie

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference