(Q39078185)

8 September 2017

Identification of biomarkers for apoptosis in cancer cell lines using metabolomics: tools for individualized medicine (English)

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8 September 2017

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3

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8 September 2017

Martin Hrabě de Angelis

series ordinal

4

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8 September 2017

A Halama

1

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author name string

N Riesen

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2

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8 September 2017

J Adamski

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5

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8 September 2017

language of work or name

English

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publication date

1 November 2013

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Journal of Internal Medicine

8 September 2017

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8 September 2017

274

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8 September 2017

425-439

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8 September 2017

5

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Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

8 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Cancer. Systems biology, metabolomics, and cancer metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Clinical steroid mass spectrometry: a 45-year history culminating in HPLC-MS/MS becoming an essential tool for patient diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

The human serum metabolome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Novel methodologies in metabolic profiling with a focus on molecular diagnostic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Extending biochemical databases by metabolomic surveys

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Human metabolic individuality in biomedical and pharmaceutical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Glycomics: a pathway to a class of new and improved therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolomics, a novel tool for studies of nutrition, metabolism and lipid dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Mass spectrometry: from proteomics to metabolomics and lipidomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Effects of sample handling and storage on quantitative lipid analysis in human serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolomics and cardiovascular biomarker discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Challenges in mass spectrometry based targeted metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Targeted metabolomics for biomarker discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

From differentiating metabolites to biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Standards, databases, and modeling tools in systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

The Chemical Translation Service--a web-based tool to improve standardization of metabolomic reports

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Systems medicine and the integration of bioinformatic tools for the diagnosis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

metaP-server: a web-based metabolomics data analysis tool

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Bayesian independent component analysis recovers pathway signatures from blood metabolomics data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Human serum metabolic profiles are age dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Discovery of sexual dimorphisms in metabolic and genetic biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

A genome-wide perspective of genetic variation in human metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

The dynamic range of the human metabolome revealed by challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Identification of a potential biomarker for FABP4 inhibition: the power of lipidomics in preclinical drug testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Reliability of serum metabolite concentrations over a 4-month period using a targeted metabolomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Genome-wide association studies with metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Molecular epidemiology and its current clinical use in cancer management

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Opportunities for studying cancer by metabolomics: preliminary observations on tumors deficient in hypoxia-inducible factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Application of metabolomics to prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolomics: a revolution for novel cancer marker identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolomics in cancer: a bench-to-bedside intersection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolic signatures of malignant progression in prostate epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Estrogens, enzyme variants, and breast cancer: a risk model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Nutrigenomics: implications for breast and colon cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Regulation of the metabolite profile by an APC gene mutation in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolite profiling of fecal water extracts from human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Serum amino acid profiles and their alterations in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

A novel serum metabolomics-based diagnostic approach for colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

A metabolomic approach to lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolomics and bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Cyclin-dependent kinases 4 and 6 control tumor progression and direct glucose oxidation in the pentose cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Hypoxia-induced metabolic shifts in cancer cells: moving beyond the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Histone deacetylase inhibition results in a common metabolic profile associated with HT29 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Characterization of 1H NMR detectable mobile lipids in cells from human adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Increases in NMR-visible lipid and glycerophosphocholine during phenylbutyrate-induced apoptosis in human prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolomics using 1H-NMR of apoptosis and Necrosis in HL60 leukemia cells: differences between the two types of cell death and independence from the stimulus of apoptosis used

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Early reduction of glucose uptake after cisplatin treatment is a marker of cisplatin sensitivity in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Noninvasive real-time imaging of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Monitoring apoptosis and neuronal degeneration by real-time detection of phosphatidylserine externalization using a polarity-sensitive indicator of viability and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Molecular recognition mechanisms for detecting cell death in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

5-Fluorouracil (5-FU) induced apoptosis in gastric cancer cell lines: role of the p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolic signatures in apoptotic human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Protein biomarkers for the early detection of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Novel biomarkers for pre-diabetes identified by metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Clinical applications of metabolomics in oncology: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolic profiling reveals distinct variations linked to nicotine consumption in humans--first results from the KORA study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Variation in the human lipidome associated with coffee consumption as revealed by quantitative targeted metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabotyping of biofluids reveals stress-based differences in gut permeability in healthy individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Cell culture metabolomics: applications and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Apoptosis in the development and treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Metabolic profiles of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Use of tandem mass spectrometry for multianalyte screening of dried blood specimens from newborns

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Evidence for an alternative glycolytic pathway in rapidly proliferating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

BRCA1 and acetyl-CoA carboxylase: the metabolic syndrome of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Rapid changes in specific estrogen binding elicited by cGMP or cAMP in cytosol from human endometrial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Studies on associations of glycolytic and glutaminolytic enzymes in MCF-7 cells: role of P36.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

The kynurenine pathway in brain tumor pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Normal human lymphocytes exhibit a wide range of methionine-dependency which is related to altered cell division but not micronucleus frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Assay Tools for Metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJOIM.12117

21 January 2018

Identifiers

DOI

10.1111/JOIM.12117

1 reference

8 September 2017

1 reference