(Q39084008)

8 September 2017

title

Transcriptome dynamics of transgene amplification in Chinese hamster ovary cells (English)

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8 September 2017

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Nandita Vishwanathan

1

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8 September 2017

Huong Le

2

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8 September 2017

Nitya M Jacob

3

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8 September 2017

Yung-Shyeng Tsao

4

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8 September 2017

Sze-Wai Ng

5

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8 September 2017

Bernard Loo

6

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8 September 2017

Zhong Liu

7

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8 September 2017

Anne Kantardjieff

8

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8 September 2017

Wei-Shou Hu

9

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8 September 2017

publication date

18 October 2013

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Biotechnology and Bioengineering

8 September 2017

published in

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8 September 2017

volume

111

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8 September 2017

issue

3

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8 September 2017

page(s)

518-528

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B- to plasma-cell terminal differentiation entails oxidative stress and profound reshaping of the antioxidant responses

8 September 2017

cites work

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A structured model for monoclonal antibody synthesis in exponentially growing and stationary phase hybridoma cells

21 January 2018

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Mining transcriptome data for function-trait relationship of hyper productivity of recombinant antibody

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A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?

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Metabolic analysis of antibody producing CHO cells in fed-batch production

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Transcriptomic analysis of clonal growth rate variation during CHO cell line development

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Analysis of alterations in gene expression after amplification of recombinant genes in CHO cells

21 January 2018

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Selection strategies for the establishment of recombinant Chinese hamster ovary cell line with dihydrofolate reductase-mediated gene amplification

21 January 2018

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Transcriptome and proteome analysis of Chinese hamster ovary cells under low temperature and butyrate treatment

21 January 2018

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Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences

21 January 2018

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Coamplification and coexpression of human tissue-type plasminogen activator and murine dihydrofolate reductase sequences in Chinese hamster ovary cells

21 January 2018

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Key determinants in the occurrence of clonal variation in humanized antibody expression of cho cells during dihydrofolate reductase mediated gene amplification

21 January 2018

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CHO cells in biotechnology for production of recombinant proteins: current state and further potential

21 January 2018

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Analysis of IgG heavy chain to light chain ratio with mutant Encephalomyocarditis virus internal ribosome entry site

21 January 2018

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An empirical modeling platform to evaluate the relative control discrete CHO cell synthetic processes exert over recombinant monoclonal antibody production process titer.

21 January 2018

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Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene.

21 January 2018

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Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells.

21 January 2018

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Cell line-specific control of recombinant monoclonal antibody production by CHO cells.

21 January 2018

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Effect of cloned gene dosage on cell growth and hepatitis B surface antigen synthesis and secretion in recombinant CHO cells

21 January 2018

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On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells.

21 January 2018

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In pursuit of a super producer-alternative paths to high producing recombinant mammalian cells

21 January 2018

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Molecular portrait of high productivity in recombinant NS0 cells

21 January 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

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Significance analysis of microarrays applied to the ionizing radiation response

21 January 2018

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Gene expression profiling reveals a highly specialized genetic program of plasma cells

21 January 2018

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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

21 January 2018

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Redox remodeling allows and controls B-cell activation and differentiation

21 January 2018

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Production of recombinant protein therapeutics in cultivated mammalian cells

21 January 2018

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Genomic and proteomic exploration of CHO and hybridoma cells under sodium butyrate treatment

21 January 2018

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Comparative transcriptome analysis to unveil genes affecting recombinant protein productivity in mammalian cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIT.25117

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8 September 2017

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