(Q39087778)

9 September 2017

title

AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53. (English)

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9 September 2017

author

Anne-Lise Børresen-Dale

12

Anne-Lise Børresen-Dale

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9 September 2017

4

Judy Dering

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Jennifer Goldstein

Jennifer Goldstein

5

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Ondrej Kalous

Ondrej Kalous

1

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Anita Langerød

11

Anita Langerød

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9 September 2017

Dylan Conklin

2

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9 September 2017

Amrita J Desai

3

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9 September 2017

Charles Ginther

6

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9 September 2017

Lee Anderson

7

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9 September 2017

Ming Lu

8

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9 September 2017

Teodora Kolarova

9

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9 September 2017

Mark A Eckardt

10

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9 September 2017

Dennis J Slamon

13

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9 September 2017

Richard S Finn

14

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9 September 2017

language of work or name

English

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publication date

5 October 2013

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Breast Cancer Research and Treatment

9 September 2017

published in

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9 September 2017

volume

141

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9 September 2017

issue

3

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9 September 2017

page(s)

397-408

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The cellular geography of aurora kinases

9 September 2017

cites work

1 reference

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21 January 2018

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21 January 2018

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Inhibiting aurora kinases reduces tumor growth and suppresses tumor recurrence after chemotherapy in patient-derived triple-negative breast cancer xenografts

21 January 2018

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21 January 2018

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PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

21 January 2018

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Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro

21 January 2018

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Dacomitinib (PF-00299804), an irreversible Pan-HER inhibitor, inhibits proliferation of HER2-amplified breast cancer cell lines resistant to trastuzumab and lapatinib

21 January 2018

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Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Aurora kinase A inhibition leads to p73-dependent apoptosis in p53-deficient cancer cells

21 January 2018

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The Aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function

21 January 2018

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A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.

21 January 2018

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Targets and effectors of the cellular response to aurora kinase inhibitor MK-0457 (VX-680) in imatinib sensitive and resistant chronic myelogenous leukemia

21 January 2018

1 reference

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Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways

21 January 2018

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Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.

21 January 2018

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The FLT3 internal tandem duplication mutation is a secondary target of the aurora B kinase inhibitor AZD1152-HQPA in acute myelogenous leukemia cells

21 January 2018

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The in vitro and in vivo effects of JNJ-7706621: a dual inhibitor of cyclin-dependent kinases and aurora kinases

21 January 2018

1 reference

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Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib)

21 January 2018

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BPR1K653, a novel Aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells

21 January 2018

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Sensitivity of BRCA2 mutated human cell lines to Aurora kinase inhibition

21 January 2018

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Transcriptional analysis of the Aurora inhibitor Danusertib leading to biomarker identification in TP53 wild type cells

21 January 2018

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Mechanism of action of the Aurora kinase inhibitor CCT129202 and in vivo quantification of biological activity

21 January 2018

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Evaluation of arrayed primer extension for TP53 mutation detection in breast and ovarian carcinomas

21 January 2018

1 reference

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10.1007/S10549-013-2702-Z

21 January 2018

Identifiers

DOI

1 reference

9 September 2017

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