(Q39093774)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24053224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Off-pathway α-synuclein oligomers seem to alter α-synuclein turnover in a cell model but lack seeding capability in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24053224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

Tiago Fleming Outeiro

11

1 reference

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22 February 2020

14

Martin Ingelsson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24053224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

13

Lars Lannfelt

1 reference

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22 February 2020

author name string

Therese Fagerqvist

1

1 reference

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22 February 2020

Thomas Näsström

2

1 reference

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22 February 2020

Elisabet Ihse

3

1 reference

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22 February 2020

Veronica Lindström

4

1 reference

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22 February 2020

Charlotte Sahlin

5

1 reference

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22 February 2020

Stina M Fangmark Tucker

6

1 reference

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22 February 2020

Alex Kasaryan

7

1 reference

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22 February 2020

Mikael Karlsson

8

1 reference

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22 February 2020

Fredrik Nikolajeff

9

1 reference

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22 February 2020

Heinrich Schell

10

1 reference

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22 February 2020

Philipp J Kahle

12

1 reference

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22 February 2020

Joakim Bergström

15

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22 February 2020

publication date

20 September 2013

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22 February 2020

1 reference

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22 February 2020

volume

20

1 reference

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22 February 2020

issue

4

1 reference

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22 February 2020

page(s)

233-244

1 reference

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Alpha-synuclein in Lewy bodies

22 February 2020

cites work

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro

21 January 2018

1 reference

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Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis

21 January 2018

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A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration.

21 January 2018

1 reference

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Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Evidence for a partially folded intermediate in alpha-synuclein fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Formation of toxic oligomeric alpha-synuclein species in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links alpha-synuclein causing rapid formation of stable oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

The paraffin-embedded tissue blot detects PrP(Sc) early in the incubation time in prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Dopamine and the dopamine oxidation product 5,6-dihydroxylindole promote distinct on-pathway and off-pathway aggregation of alpha-synuclein in a pH-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Clearance and deposition of extracellular alpha-synuclein aggregates in microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

Monoclonal antibodies selective for α-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α-synuclein transgenic mice with the disease-causing A30P mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F13506129.2013.835726

10.3109/13506129.2013.835726

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24053224%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference