(Q39098938)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

HER2/neu gene amplification determines the sensitivity of uterine serous carcinoma cell lines to AZD8055, a novel dual mTORC1/2 inhibitor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

Uterine serous carcinoma

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Diana P English

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Dana M Roque

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Luisa Carrara

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Stefania Bellone

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Emiliano Cocco

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Ileana Bortolomai

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Peter E Schwartz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Thomas Rutherford

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Alessandro D Santin

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

language of work or name

English

0 references

publication date

4 September 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

131

1 reference

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20 February 2020

issue

3

1 reference

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20 February 2020

page(s)

753-758

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24012800%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

cites work

Cancer statistics, 2013

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Two pathogenetic types of endometrial carcinoma

7 January 2021

1 reference

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The management of serous papillary uterine cancer

7 January 2021

1 reference

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Uterine papillary serous and clear cell carcinomas predict for poorer survival compared to grade 3 endometrioid corpus cancers

7 January 2021

1 reference

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HER2 expression beyond breast cancer: therapeutic implications for gynecologic malignancies

7 January 2021

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Therapeutic targets: MTOR and related pathways

7 January 2021

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Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling

7 January 2021

1 reference

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Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Endoplasmic reticulum is a main localization site of mTORC2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Endoplasmic reticulum and Golgi localization sequences for mammalian target of rapamycin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Benefits of mTOR kinase targeting in oncology: pre-clinical evidence with AZD8055.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Simultaneous inhibition of mTORC1 and mTORC2 by mTOR kinase inhibitor AZD8055 induces autophagy and cell death in cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Differential sensitivity to platinum-based chemotherapy in primary uterine serous papillary carcinoma cell lines with high vs low HER-2/neu expression in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Tubulin-β-III overexpression by uterine serous carcinomas is a marker for poor overall survival after platinum/taxane chemotherapy and sensitivity to epothilones.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033

Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YGYNO.2013.08.033