(Q39100413)

English

Human Cytomegalovirus Requires Epidermal Growth Factor Receptor Signaling To Enter and Initiate the Early Steps in the Establishment of Latency in CD34+ Human Progenitor Cells.

scientific article published on 14 December 2016

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29 March 2020

Human Cytomegalovirus Requires Epidermal Growth Factor Receptor Signaling To Enter and Initiate the Early Steps in the Establishment of Latency in CD34+ Human Progenitor Cells (English)

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29 March 2020

Cytomegalovirus

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Andrew D Yurochko

5

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29 March 2020

Donna Collins-McMillen

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Donna Collins-McMillen

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29 March 2020

Felicia Goodrum

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Felicia D Goodrum

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29 March 2020

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Jung Heon Kim

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29 March 2020

Jason C Buehler

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29 March 2020

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14 February 2017

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29 March 2020

Journal of Virology

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29 March 2020

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29 March 2020

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29 March 2020

Human Cytomegalovirus Latency: Approaching the Gordian Knot

1 reference

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9 September 2017

Viral binding-induced signaling drives a unique and extended intracellular trafficking pattern during infection of primary monocytes

1 reference

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9 September 2017

Opposing Regulation of the EGF Receptor: A Molecular Switch Controlling Cytomegalovirus Latency and Replication.

1 reference

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9 September 2017

Human Cytomegalovirus Promotes Survival of Infected Monocytes via a Distinct Temporal Regulation of Cellular Bcl-2 Family Proteins

1 reference

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9 September 2017

Dynamics of virus-receptor interactions in virus binding, signaling, and endocytosis

1 reference

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9 September 2017

Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway

1 reference

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9 September 2017

TGF-β signaling in the control of hematopoietic stem cells

1 reference

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9 September 2017

Human cytomegalovirus riding the cell cycle.

1 reference

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9 September 2017

Sleepless latency of human cytomegalovirus

1 reference

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9 September 2017

Complex expression of the UL136 gene of human cytomegalovirus results in multiple protein isoforms with unique roles in replication.

1 reference

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9 September 2017

The intimate relationship between human cytomegalovirus and the dendritic cell lineage

1 reference

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9 September 2017

Randomized comparison of single dose of recombinant human IL-12 versus placebo for restoration of hematopoiesis and improved survival in rhesus monkeys exposed to lethal radiation

1 reference

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9 September 2017

Cytomegalovirus miRNAs target secretory pathway genes to facilitate formation of the virion assembly compartment and reduce cytokine secretion.

1 reference

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9 September 2017

Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection

1 reference

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9 September 2017

HCMV reprogramming of infected monocyte survival and differentiation: a Goldilocks phenomenon

1 reference

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9 September 2017

Cytomegalovirus infections in solid organ transplantation: a review

1 reference

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9 September 2017

Human cytomegalovirus latency-associated proteins elicit immune-suppressive IL-10 producing CD4⁺ T cells

1 reference

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9 September 2017

The HCMV gH/gL/UL128-131 complex triggers the specific cellular activation required for efficient viral internalization into target monocytes

1 reference

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9 September 2017

Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells

1 reference

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9 September 2017

Human cytomegalovirus stimulates monocyte-to-macrophage differentiation via the temporal regulation of caspase 3.

1 reference

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9 September 2017

Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4+ T-cell migration and suppression of effector function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Human cytomegalovirus induction of a unique signalsome during viral entry into monocytes mediates distinct functional changes: a strategy for viral dissemination

1 reference

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9 September 2017

Interactions between proteins encoded within the human cytomegalovirus UL133-UL138 locus.

1 reference

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9 September 2017

Human cytomegalovirus persistence

1 reference

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9 September 2017

A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Detection of human cytomegalovirus in normal and neoplastic breast epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Cytomegalovirus in hematopoietic stem cell transplant recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Human cytomegalovirus-regulated paxillin in monocytes links cellular pathogenic motility to the process of viral entry

1 reference

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9 September 2017

Human cytomegalovirus immunity and immune evasion

1 reference

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9 September 2017

Experimental human cytomegalovirus latency in CD14+ monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

A viral microRNA down-regulates multiple cell cycle genes through mRNA 5'UTRs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

PI3K-dependent upregulation of Mcl-1 by human cytomegalovirus is mediated by epidermal growth factor receptor and inhibits apoptosis in short-lived monocytes

1 reference

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9 September 2017

Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motility

1 reference

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9 September 2017

NF-kappaB and phosphatidylinositol 3-kinase activity mediates the HCMV-induced atypical M1/M2 polarization of monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Characterization of a novel Golgi apparatus-localized latency determinant encoded by human cytomegalovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Aspects of human cytomegalovirus latency and reactivation

1 reference

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9 September 2017

Human cytomegalovirus modulation of signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Cytomegalovirus cell tropism.

1 reference

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9 September 2017

Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

9 September 2017

Human CMV infection of endothelial cells induces an angiogenic response through viral binding to EGF receptor and beta1 and beta3 integrins

1 reference

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9 September 2017

Human cytomegalovirus: Latency and reactivation in the myeloid lineage

1 reference

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9 September 2017

Transcriptome analysis of NF-kappaB- and phosphatidylinositol 3-kinase-regulated genes in human cytomegalovirus-infected monocytes

1 reference

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9 September 2017

Roles of phosphatidylinositol 3-kinase and NF-kappaB in human cytomegalovirus-mediated monocyte diapedesis and adhesion: strategy for viral persistence

1 reference

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9 September 2017

Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro

1 reference

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9 September 2017

The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalpha

1 reference

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9 September 2017

Human cytomegalovirus (HCMV) infection of endothelial cells promotes naive monocyte extravasation and transfer of productive virus to enhance hematogenous dissemination of HCMV

1 reference

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9 September 2017

Human cytomegalovirus infection of cells of hematopoietic origin: HCMV-induced immunosuppression, immune evasion, and latency

1 reference

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9 September 2017

Does cytomegalovirus play a causative role in the development of various inflammatory diseases and cancer?

1 reference

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9 September 2017

Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion

1 reference

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9 September 2017

Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expression

1 reference

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9 September 2017

Integrin alphavbeta3 is a coreceptor for human cytomegalovirus

1 reference

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9 September 2017

Cellular integrins function as entry receptors for human cytomegalovirus via a highly conserved disintegrin-like domain

1 reference

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9 September 2017

Activation of the NF-kappaB pathway in human cytomegalovirus-infected cells is necessary for efficient transactivation of the major immediate-early promoter

1 reference

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9 September 2017

Human cytomegalovirus induces monocyte differentiation and migration as a strategy for dissemination and persistence

1 reference

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9 September 2017

Cytomegalovirus in hematopoietic stem cell transplant recipients: current status, known challenges, and future strategies

1 reference

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9 September 2017

Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus

1 reference

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9 September 2017

Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latency

1 reference

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9 September 2017

Cytomegalovirus mediated myelosuppression

1 reference

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9 September 2017

Definitions of cytomegalovirus infection and disease in transplant recipients

1 reference

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9 September 2017

Reactivation of latent human cytomegalovirus in CD14(+) monocytes is differentiation dependent

1 reference

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9 September 2017

Human cytomegalovirus infection of human hematopoietic progenitor cells

1 reference

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9 September 2017

Cytomegalovirus inhibits the engraftment of donor bone marrow cells by downregulation of hemopoietin gene expression in recipient stroma

1 reference

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9 September 2017

Induction of endogenous human cytomegalovirus gene expression after differentiation of monocytes from healthy carriers

1 reference

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9 September 2017

Candidate cytomegalovirus strain for human vaccination

1 reference

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9 September 2017

Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34⁺ progenitors.

1 reference

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14 September 2017

Integrins as Herpesvirus Receptors and Mediators of the Host Signalosome.

1 reference

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14 September 2017

The myeloid transcription factor GATA-2 regulates the viral UL144 gene during human cytomegalovirus latency in an isolate-specific manner

1 reference

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14 September 2017

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection

1 reference

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14 September 2017

Human cytomegalovirus productively infects primary differentiated macrophages

1 reference

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14 September 2017

HCMV Induces Macropinocytosis for Host Cell Entry in Fibroblasts

1 reference

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25 September 2017

Human cytomegalovirus labeled with green fluorescent protein for live analysis of intracellular particle movements

1 reference

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25 September 2017

Cell types involved in replication and distribution of human cytomegalovirus.

1 reference

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25 September 2017

Latent and persistent infections of monocytes and macrophages

1 reference

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25 September 2017

Developmental defects in zebrafish for classification of EGF pathway inhibitors

1 reference

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15 June 2018

Entry of human cytomegalovirus into retinal pigment epithelial and endothelial cells by endocytosis

1 reference

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15 June 2018

Immunohistochemical detection of an immediate early antigen of human cytomegalovirus in normal tissues

1 reference

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15 June 2018

Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells

1 reference

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15 June 2018

Human cytomegalovirus penetrates host cells by pH-independent fusion at the cell surface

1 reference

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15 June 2018

Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line

1 reference

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15 June 2018

Small tyrosine kinase inhibitors interrupt EGFR signaling by interacting with erbB3 and erbB4 in glioblastoma cell lines.

1 reference

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21 August 2018

The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients

1 reference

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21 August 2018

Off-target effects of epidermal growth factor receptor antagonists mediate retinal ganglion cell disinhibited axon growth

1 reference

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21 August 2018

IL-12 facilitates both the recovery of endogenous hematopoiesis and the engraftment of stem cells after ionizing radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

21 August 2018

Human cytomegalovirus infection and expression in human malignant glioma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

21 August 2018

Direct inhibition of the cloned Kv1.5 channel by AG-1478, a tyrosine kinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

21 August 2018

High risk of death due to bacterial and fungal infection among cytomegalovirus (CMV)-seronegative recipients of stem cell transplants from seropositive donors: evidence for indirect effects of primary CMV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

21 August 2018

Spread of human cytomegalovirus (HCMV) after infection of human hematopoietic progenitor cells: model of HCMV latency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5309964

21 August 2018

Detection of endogenous human cytomegalovirus in CD34+ bone marrow progenitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Late cytomegalovirus disease and mortality in recipients of allogeneic hematopoietic stem cell transplants: importance of viral load and T-cell immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytomegalovirus and marrow function

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cytomegalovirus suppression of and latency in early hematopoietic progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High rate of concurrent genital infections with human cytomegalovirus and human papillomaviruses in cervical cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutropenia in allogeneic marrow transplant recipients receiving ganciclovir for prevention of cytomegalovirus disease: risk factors and outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymerase chain reaction for detection of human cytomegalovirus infection in a blood donor population

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread presence of histologically occult cytomegalovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection of mononucleated phagocytes with human cytomegalovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HCMV activates PI(3)K in monocytes and promotes monocyte motility and transendothelial migration in a PI(3)K-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/27974567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01206-16

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27974567%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27974567%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27974567%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

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