(Q39130783)

9 September 2017

title

Lovastatin-induced apoptosis is mediated by activating transcription factor 3 and enhanced in combination with salubrinal (English)

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9 September 2017

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ChEBI release 2020-05-28

Nima Niknejad

1

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9 September 2017

Ivan Gorn-Hondermann

2

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9 September 2017

Laurie Ma

3

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9 September 2017

Stephanie Zahr

4

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9 September 2017

Stephanie Johnson-Obeseki

5

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9 September 2017

Martin Corsten

6

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9 September 2017

Jim Dimitroulakos

7

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9 September 2017

language of work or name

English

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publication date

1 August 2013

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International Journal of Cancer

9 September 2017

number of pages

12

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based on heuristic

inferred from page(s)

published in

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9 September 2017

volume

134

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9 September 2017

issue

2

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9 September 2017

page(s)

268-279

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Cholesterol inhibition, cancer, and chemotherapy

9 September 2017

cites work

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HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis

21 January 2018

1 reference

Pharmacology of competitive inhibitors of HMG-CoA reductase.

21 January 2018

1 reference

3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis

21 January 2018

1 reference

A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix

21 January 2018

1 reference

Activation of the integrated stress response regulates lovastatin-induced apoptosis

21 January 2018

1 reference

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

21 January 2018

1 reference

21 January 2018

All roads lead to ATF4

1 reference

Coping with stress: eIF2 kinases and translational control

21 January 2018

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Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

21 January 2018

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Translational control in stress and apoptosis

21 January 2018

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The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis

21 January 2018

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Activating transcription factor 4 is translationally regulated by hypoxic stress

21 January 2018

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Cisplatin induces cytotoxicity through the mitogen-activated protein kinase pathways and activating transcription factor 3.

21 January 2018

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Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor

21 January 2018

1 reference

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

21 January 2018

1 reference

Metronomic dosing of BH3 mimetic small molecule yields robust antiangiogenic and antitumor effects

21 January 2018

1 reference

Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins

21 January 2018

1 reference

Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells

21 January 2018

1 reference

Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas

21 January 2018

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Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress.

21 January 2018

1 reference

Apoptosis and necrosis: detection, discrimination and phagocytosis

21 January 2018

1 reference

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death

21 January 2018

1 reference

The regulation of ATF3 gene expression by mitogen-activated protein kinases

21 January 2018

1 reference

Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesis

21 January 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 January 2018

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Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene

21 January 2018

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Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response

21 January 2018

1 reference

Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

21 January 2018

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gadd153/Chop10, a potential target gene of the transcriptional repressor ATF3.

21 January 2018

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Synergistic apoptosis induction in leukemic cells by the phosphatase inhibitor salubrinal and proteasome inhibitors

21 January 2018

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Inhibition of eIF2alpha dephosphorylation maximizes bortezomib efficiency and eliminates quiescent multiple myeloma cells surviving proteasome inhibitor therapy

21 January 2018

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Activating Transcription Factor 3 regulates in part the enhanced tumour cell cytotoxicity of the histone deacetylase inhibitor M344 and cisplatin in combination

21 January 2018

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Regulation of the mevalonate pathway

21 January 2018

1 reference

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.28369

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release_sm6xlylwanh6tgjn6y5g2cttcq

9 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sm6xlylwanh6tgjn6y5g2cttcq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference