(Q39135323)

9 September 2017

Computational prediction of drug solubility in fasted simulated and aspirated human intestinal fluid (English)

1 reference

9 September 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Eva Karlsson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Johan Ulander

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Gunilla Hanisch

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Christel A S Bergström

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

publication date

4 September 2014

1 reference

9 September 2017

Pharmaceutical Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

578-589

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

31 May 2020

copyright license

start time

4 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Computational prediction of drug solubility in lipid based formulation excipients.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Target promiscuity and physicochemical properties contribute to pharmacologically induced ER-stress

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Getting physical in drug discovery II: the impact of chromatographic hydrophobicity measurements and aromaticity

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Recent advances on aqueous solubility prediction

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Physiochemical drug properties associated with in vivo toxicological outcomes

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Profiling and trend analysis of food effects on oral drug absorption considering micelle interaction and solubilization by bile micelles

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

A modified physiological BCS for prediction of intestinal absorption in drug discovery.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Molecular dynamics simulations of functional group effects on solvation thermodynamics of model solutes in decane and tricaprylin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Dissolution media simulating conditions in the proximal human gastrointestinal tract: an update

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Glyceride lipid formulations: molecular dynamics modeling of phase behavior during dispersion and molecular interactions between drugs and excipients

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Solubility profiling of HIV protease inhibitors in human intestinal fluids

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Computational prediction of CNS drug exposure based on a novel in vivo dataset.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Ethanol effects on apparent solubility of poorly soluble drugs in simulated intestinal fluid.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Revisiting the general solubility equation: in silico prediction of aqueous solubility incorporating the effect of topographical polar surface area.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Intestinal drug solubility estimation based on simulated intestinal fluids: comparison with solubility in human intestinal fluids.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Simulating fasted human intestinal fluids: understanding the roles of lecithin and bile acids.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

What is modulating solubility in simulated intestinal fluids?

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Dissolution rate and apparent solubility of poorly soluble drugs in biorelevant dissolution media.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Rate-limiting steps of oral absorption for poorly water-soluble drugs in dogs; prediction from a miniscale dissolution test and a physiologically-based computer simulation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

The influence of drug-like concepts on decision-making in medicinal chemistry

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Accuracy of calculated pH-dependent aqueous drug solubility.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Dissolution media simulating the intralumenal composition of the small intestine: physiological issues and practical aspects.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Prediction of drug solubility by the general solubility equation (GSE).

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

The correlation and prediction of the solubility of compounds in water using an amended solvation energy relationship.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Solubility and partitioning I: Solubility of nonelectrolytes in water.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4300419

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11095-014-1487-Z

Global and Local Computational Models for Aqueous Solubility Prediction of Drug-Like Molecules

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25186438

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effects of food on the dissolution of poorly soluble drugs in human and in model small intestinal fluids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25186438

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25186438

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11095-014-1487-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

25186438

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25186438%20AND%20SRC:MED&resulttype=core&format=json