(Q46534443)

English

Rate-limiting steps of oral absorption for poorly water-soluble drugs in dogs; prediction from a miniscale dissolution test and a physiologically-based computer simulation.

scientific article published on 17 June 2008

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Rate-limiting steps of oral absorption for poorly water-soluble drugs in dogs; prediction from a miniscale dissolution test and a physiologically-based computer simulation (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

computer simulation

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based on heuristic

inferred from title

Noriyuki Takata

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Ryusuke Takano

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Kentaro Furumoto

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Koji Shiraki

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Yoshiki Hayashi

5

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Europe PubMed Central

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9 January 2020

Yoshinori Aso

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Shinji Yamashita

7

1 reference

Europe PubMed Central

PubMed publication ID

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9 January 2020

publication date

17 June 2008

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

25

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9 January 2020

10

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9 January 2020

2334-2344

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Physiological measurements of luminal stirring in the dog and human small bowel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro system to evaluate oral absorption of poorly water-soluble drugs: simultaneous analysis on dissolution and permeation of drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unstirred layer thickness in perfused rat jejunum in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of oral drug absorption in humans by theoretical passive absorption model

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calculation of the aqueous diffusion layer resistance for absorption in a tube: application to intestinal membrane permeability determination

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canine intestinal contents vs. simulated media for the assessment of solubility of two weak bases in the human small intestinal contents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aqueous solubility and dissolution rate does not adequately predict in vivo performance: a probe utilizing some N-acyloxymethyl phenytoin prodrugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancing intestinal drug solubilisation using lipid-based delivery systems.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting the impact of physiological and biochemical processes on oral drug bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improving the dissolution rate of poorly water soluble drug by solid dispersion and solid solution: pros and cons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane transport of drugs in different regions of the intestinal tract of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of carbon monoxide to measure luminal stirring in the rat gut.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologically-based pharmacokinetic simulation modelling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Closed rat jejunal segment in situ: role of pre-epithelial diffusion resistance (unstirred layer) in the absorption process and model analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular properties of WHO essential drugs and provisional biopharmaceutical classification

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of canine and human gastrointestinal physiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral absorption of poorly water-soluble drugs: computer simulation of fraction absorbed in humans from a miniscale dissolution test.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human intestinal permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rate-limiting barriers to intestinal drug absorption: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Can the USP paddle method be used to represent in-vivo hydrodynamics?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An integrated model for determining causes of poor oral drug absorption.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solubility and dissolution profile assessment in drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-like properties and the causes of poor solubility and poor permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Theoretical dissolution model of poly-disperse drug particles in biorelevant media.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18560998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-008-9637-9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18560998%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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