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The Pak4 protein kinase is required for oncogenic transformation of MDA-MB-231 breast cancer cells.
scientific article published on 3 June 2013
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
title
The Pak4 protein kinase is required for oncogenic transformation of MDA-MB-231 breast cancer cells
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
author
Ning Chen
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
author name string
L E Wong
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
V Karantza
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
A Minden
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
language of work or name
English
1 reference
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publication date
3 June 2013
1 reference
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Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
published in
Oncogenesis
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
page(s)
e50
1 reference
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Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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PubMed Central
reference URL
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A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells
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The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis.
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p120-catenin is a binding partner and substrate for Group B Pak kinases
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Pak protein kinases and their role in cancer
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The pak4 protein kinase plays a key role in cell survival and tumorigenesis in athymic mice
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UnPAKing the class differences among p21-activated kinases
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The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis
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10 September 2017
PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia
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ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression.
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10 September 2017
PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor
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Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4.
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17 June 2018
Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines
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17 June 2018
PAK1 hyperactivation is sufficient for mammary gland tumor formation
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21 August 2018
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.
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Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1
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21 January 2018
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21 January 2018
Identifiers
DOI
10.1038/ONCSIS.2013.13
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
Fatcat ID
release_uhucnlohlbdh5p5yjx2rbo3ynu
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/uhucnlohlbdh5p5yjx2rbo3ynu
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3740299
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
PubMed publication ID
23732710
1 reference
stated in
Europe PubMed Central
PMC publication ID
3740299
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23732710%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
ResearchGate publication ID
237016902
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