(Q39146122)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

title

Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

1 reference

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Zhiping Liu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

author name string

Liangmei He

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Yayun Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Yuanbing Wu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Ying Xu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Zixiang Zhang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

publication date

21 February 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

Cellular and Molecular Life Sciences

3 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

volume

74

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

page(s)

2395-2411

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

Global cancer statistics, 2012

3 April 2020

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NOD-like receptors in intestinal homeostasis and epithelial tissue repair

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21 January 2018

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21 January 2018

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Role of Nlrp6 and Nlrp12 in the maintenance of intestinal homeostasis

21 January 2018

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The application of Toll like receptors for cancer therapy

21 January 2018

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Toll-like receptor genes and their association with colon and rectal cancer development and prognosis

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Epithelial toll-like receptor 9 signaling in colorectal inflammation and cancer: clinico-pathogenic aspects

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Contribution of TLR signaling to the pathogenesis of colitis-associated cancer in inflammatory bowel disease

21 January 2018

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An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology

21 January 2018

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

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IFI16 is an innate immune sensor for intracellular DNA

21 January 2018

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IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

21 January 2018

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The Nlrp3 inflammasome: contributions to intestinal homeostasis

21 January 2018

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The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.

21 January 2018

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Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma

21 January 2018

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AIM2, an IFN-inducible cytosolic DNA sensor, in the development of benign prostate hyperplasia and prostate cancer

21 January 2018

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Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma

21 January 2018

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DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndrome.

21 January 2018

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The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers

21 January 2018

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The landscape of microsatellite instability in colorectal and endometrial cancer genomes

21 January 2018

1 reference

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Inflammasomes: mechanism of action, role in disease, and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt

21 January 2018

1 reference

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Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

21 January 2018

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Murine Model for Colitis-Associated Cancer of the Colon

21 January 2018

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Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Stem cells, self-renewal, and differentiation in the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Crypt stem cells as the cells-of-origin of intestinal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

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The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense.

21 January 2018

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AIM2 contributes to the maintenance of intestinal integrity via Akt and protects against Salmonella mucosal infection

21 January 2018

1 reference

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The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway

21 January 2018

1 reference

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The detection and implication of genome instability in cancer

21 January 2018

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STING is a direct innate immune sensor of cyclic di-GMP

21 January 2018

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Cyclic di-nucleotide signaling enters the eukaryote domain.

21 January 2018

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

21 January 2018

1 reference

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

21 January 2018

1 reference

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cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

21 January 2018

1 reference

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Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

21 January 2018

1 reference

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Activation of STAT6 by STING is critical for antiviral innate immunity

21 January 2018

1 reference

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Cutting edge: STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Diverse roles of STING-dependent signaling on the development of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Human plasmacytoid dentritic cells elicit a Type I Interferon response by sensing DNA via the cGAS-STING signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Growing tumors induce a local STING dependent Type I IFN response in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

The role of DNA methylation in the pathogenesis and treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Oncotarget Strategies For Herpes Simplex Virus-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

DExD/H box RNA helicases: from generic motors to specific dissociation functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Immune signaling by RIG-I-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

SnapShot: Nucleic acid immune sensors, part 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling West Nile virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Rig-I-/- mice develop colitis associated with downregulation of G alpha i2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Transcriptional activation of the human Galphai2 gene promoter through nuclear factor-kappaB and antioxidant response elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Selective downregulation of retinoic acid-inducible gene I within the intestinal epithelial compartment in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Essential contribution of IRF3 to intestinal homeostasis and microbiota-mediated Tslp gene induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Cellular DDX21 RNA helicase inhibits influenza A virus replication but is counteracted by the viral NS1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

The DEAD-box RNA helicase DDX6 is required for efficient encapsidation of a retroviral genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Germline heterozygous DDX41 variants in a subset of familial myelodysplasia and acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Two novel germline DDX41 mutations in a family with inherited myelodysplasia/acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Re-emergence of acute myeloid leukemia in donor cells following allogeneic transplantation in a family with a germline DDX41 mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

The AZFa gene DBY (DDX3Y) is widely transcribed but the protein is limited to the male germ cells by translation control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

21 January 2018

Wnt signaling in cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-β-catenin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Systematic review of the old and new concepts in the epithelial-mesenchymal transition of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Oncogenic role of DDX3 in breast cancer biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Nuclear DNA helicase II unwinds both DNA and RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Conserved recurrent gene mutations correlate with pathway deregulation and clinical outcomes of lung adenocarcinoma in never-smokers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

DEAD box RNA helicase functions in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Overexpression and poly-ubiquitylation of the DEAD-box RNA helicase p68 in colorectal tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Overexpression of rck/p54, a DEAD box protein, in human colorectal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Knockdown of RCK/p54 expression by RNAi inhibits proliferation of human colorectal cancer cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

The novel G-quadruplex-containing long non-coding RNA GSEC antagonizes DHX36 and modulates colon cancer cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-017-2477-1

Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia

21 January 2018

1 reference

12 December 2020

CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer

1 reference

12 December 2020

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

1 reference

12 December 2020

Involvement of RNA helicases p68 and p72 in colon cancer

1 reference

12 December 2020

In Vivo Selection Against Human Colorectal Cancer Xenografts Identifies an Aptamer That Targets RNA Helicase Protein DHX9.

1 reference

12 December 2020

Toll-like receptor signaling in colorectal cancer: carcinogenesis to cancer therapy.

1 reference

12 December 2020

DDX3 enhances oncogenic KRAS‑induced tumor invasion in colorectal cancer via the β‑catenin/ZEB1 axis

1 reference

12 December 2020

Molecular cloning and characterization of human DDX36 and mouse Ddx36 genes, new members of the DEAD/H box superfamily

1 reference

12 December 2020

DDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancer

1 reference

12 December 2020

Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9.

1 reference

12 December 2020

Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells

1 reference

12 December 2020

Analysis of the RNA helicase A gene in human lung cancer

1 reference

12 December 2020

Activated STING enhances Tregs infiltration in the HPV-related carcinogenesis of tongue squamous cells via the c-jun/CCL22 signal

1 reference

12 December 2020

Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.

1 reference

12 December 2020

10.1007/S00018-017-2477-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28224203%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference