(Q39168299)

9 September 2017

title

A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation (English)

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9 September 2017

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Andreas Natsch

1

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9 September 2017

Cindy A Ryan

2

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9 September 2017

Leslie Foertsch

3

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9 September 2017

Roger Emter

4

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9 September 2017

Joanna Jaworska

5

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9 September 2017

Frank Gerberick

6

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9 September 2017

Petra Kern

7

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9 September 2017

language of work or name

English

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publication date

9 April 2013

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Journal of Applied Toxicology

9 September 2017

published in

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9 September 2017

volume

33

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9 September 2017

issue

11

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9 September 2017

page(s)

1337-1352

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Activation of U937 cells by contact sensitizers: CD86 expression is independent of apoptosis

9 September 2017

cites work

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Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients

21 January 2018

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Development of an in vitro skin sensitization test using human cell lines: the human Cell Line Activation Test (h-CLAT). I. Optimization of the h-CLAT protocol

21 January 2018

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Evaluating the sensitization potential of surfactants: integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach.

21 January 2018

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Local lymph node assay - validation, conduct and use in practice

21 January 2018

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Updating the skin sensitization in vitro data assessment paradigm in 2009.

21 January 2018

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Identification and classification of skin sensitizers: identifying false positives and false negatives

21 January 2018

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An evaluation of the suitability of benzocaine as a positive control skin sensitizer

21 January 2018

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Putting the parts together: combining in vitro methods to test for skin sensitizing potentials

21 January 2018

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Structure--activity relationship between the in vivo skin sensitizing potency of analogues of phenyl glycidyl ether and the induction of Nrf2-dependent luciferase activity in the KeratinoSens in vitro assay

21 January 2018

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Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.

21 January 2018

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Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system

21 January 2018

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Development of a peptide reactivity assay for screening contact allergens

21 January 2018

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Quantification of chemical peptide reactivity for screening contact allergens: a classification tree model approach

21 January 2018

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A cell-based in vitro alternative to identify skin sensitizers by gene expression

21 January 2018

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Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice.

21 January 2018

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A future approach to measuring relative skin sensitising potency: a proposal

21 January 2018

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Use of diethyl squarate for the coupling of oligosaccharide amines to carrier proteins and characterization of the resulting neoglycoproteins by MALDI-TOF mass spectrometry

21 January 2018

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Classification of contact allergens according to potency: proposals

21 January 2018

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Assessment of chemical skin-sensitizing potency by an in vitro assay based on human dendritic cells

21 January 2018

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A new in vitro method for identifying chemical sensitizers combining peptide binding with ARE/EpRE-mediated gene expression in human skin cells

21 January 2018

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Non-animal test methods for predicting skin sensitization potentials

21 January 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

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The Nrf2-Keap1-ARE toxicity pathway as a cellular sensor for skin sensitizers--functional relevance and a hypothesis on innate reactions to skin sensitizers.

21 January 2018

1 reference

Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing

21 January 2018

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Relating skin sensitizing potency to chemical reactivity: reactive Michael acceptors inhibit NF-κB signaling and are less sensitizing than S(N)Ar- and S(N)2- reactive chemicals

21 January 2018

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What determines skin sensitization potency-myths, maybes and realities. Part 1. The 500 molecular weight cut-off

21 January 2018

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High throughput kinetic profiling approach for covalent binding to peptides: application to skin sensitization potency of Michael acceptor electrophiles.

21 January 2018

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Risk of sensitization to preservatives estimated on the basis of patch test data and exposure, according to a sample of 3541 leave-on products

21 January 2018

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Contact allergy to fragrances: current patch test results (2005-2008) from the Information Network of Departments of Dermatology

21 January 2018

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Applicability of a keratinocyte gene signature to predict skin sensitizing potential

21 January 2018

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Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds.

21 January 2018

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Squaric acid mediated synthesis and biological activity of a library of linear and hyperbranched poly(glycerol)-protein conjugates

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JAT.2868

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9 September 2017

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