(Q39179266)

9 September 2017

Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib (English)

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9 September 2017

hepatocellular carcinoma

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6

Bruno Chauffert

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author name string

Christophe Louandre

1

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9 September 2017

Zakaria Ezzoukhry

2

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9 September 2017

Corinne Godin

3

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9 September 2017

Jean-Claude Barbare

4

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9 September 2017

Jean-Claude Mazière

5

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9 September 2017

Antoine Galmiche

7

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9 September 2017

language of work or name

English

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publication date

8 April 2013

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International Journal of Cancer

9 September 2017

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9 September 2017

133

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9 September 2017

7

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9 September 2017

1732-1742

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9 September 2017

Hepatocellular carcinoma

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Sorafenib in advanced hepatocellular carcinoma

21 January 2018

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Targeted therapies for hepatocellular carcinoma.

21 January 2018

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Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

21 January 2018

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BAD, a proapoptotic member of the BCL2 family, is a potential therapeutic target in hepatocellular carcinoma

21 January 2018

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The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib

21 January 2018

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Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli.

21 January 2018

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Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis

21 January 2018

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Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

21 January 2018

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Sorafenib induces preferential apoptotic killing of a drug- and radio-resistant Hep G2 cells through a mitochondria-dependent oxidative stress mechanism

21 January 2018

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Advances in metal-induced oxidative stress and human disease

21 January 2018

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Regulation of cellular iron metabolism

21 January 2018

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Isoform-specific interaction of C-RAF with mitochondria

21 January 2018

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Specific iron chelators determine the route of ferritin degradation

21 January 2018

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Involvement of receptor tyrosine phosphatase DEP-1 mediated PI3K-cofilin signaling pathway in sorafenib-induced cytoskeletal rearrangement in hepatoma cells.

21 January 2018

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Anthrax lethal factor proteolysis and inactivation of MAPK kinase.

21 January 2018

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C11-BODIPY(581/591), an oxidation-sensitive fluorescent lipid peroxidation probe: (micro)spectroscopic characterization and validation of methodology

21 January 2018

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Ferroptosis: an iron-dependent form of nonapoptotic cell death

21 January 2018

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Lipid peroxides and human diseases

21 January 2018

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Iron deprivation suppresses hepatocellular carcinoma growth in experimental studies.

21 January 2018

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Iron chelation-induced senescence-like growth arrest in hepatocyte cell lines: association of transforming growth factor beta1 (TGF-beta1)-mediated p27Kip1 expression.

21 January 2018

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Modulatory profiling identifies mechanisms of small molecule-induced cell death.

21 January 2018

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Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver

21 January 2018

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Expression of hepcidin mRNA is uniformly suppressed in hepatocellular carcinoma

21 January 2018

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Modulation of iron-regulatory genes in human hepatocellular carcinoma and its physiological consequences.

21 January 2018

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Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis

21 January 2018

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Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis

21 January 2018

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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

21 January 2018

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Association of reactive oxygen species levels and radioresistance in cancer stem cells

21 January 2018

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Vitamin K enhancement of sorafenib-mediated HCC cell growth inhibition in vitro and in vivo

21 January 2018

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Oxygen free radical generating mechanisms in the colon: do the semiquinones of vitamin K play a role in the aetiology of colon cancer?

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.28159

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9 September 2017

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