(Q39486469)

12 September 2017

title

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma (English)

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12 September 2017

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4

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12 September 2017

13

Tamotsu Yoshimori

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12 September 2017

2

Tetsuo Takehara

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12 September 2017

11

Naoki Hiramatsu

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12 September 2017

9

Tomohide Tatsumi

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12 September 2017

6

Takuya Miyagi

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12 September 2017

Satoshi Shimizu

1

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12 September 2017

Hayato Hikita

3

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12 September 2017

Hinako Tsunematsu

5

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12 September 2017

Atsushi Hosui

7

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12 September 2017

Hisashi Ishida

8

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12 September 2017

Tatsuya Kanto

10

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12 September 2017

Naonobu Fujita

12

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12 September 2017

Norio Hayashi

14

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12 September 2017

language of work or name

English

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publication date

12 September 2011

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International Journal of Cancer

12 September 2017

number of pages

10

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based on heuristic

inferred from page(s)

published in

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12 September 2017

volume

131

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12 September 2017

issue

3

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12 September 2017

page(s)

548-557

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12 September 2017

cites work

Drug therapy: sorafenib

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Sorafenib in advanced hepatocellular carcinoma

21 January 2018

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Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

21 January 2018

1 reference

Autophagy: a regulated bulk degradation process inside cells

21 January 2018

1 reference

Another way to die: autophagic programmed cell death

21 January 2018

1 reference

The double-edged sword of autophagy modulation in cancer

21 January 2018

1 reference

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

21 January 2018

1 reference

The role of autophagy in cancer development and response to therapy.

21 January 2018

1 reference

Sorafenib induces apoptosis and autophagy in prostate cancer cells in vitro.

21 January 2018

1 reference

Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation

21 January 2018

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Sorafenib Activates CD95 and Promotes Autophagy and Cell Death via Src Family Kinases in Gastrointestinal Tumor Cells

21 January 2018

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The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma

21 January 2018

1 reference

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

21 January 2018

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The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib

21 January 2018

1 reference

How to interpret LC3 immunoblotting

21 January 2018

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

Raf kinase as a target for anticancer therapeutics

21 January 2018

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Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

21 January 2018

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Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2.

21 January 2018

1 reference

The role of TOR in autophagy regulation from yeast to plants and mammals

21 January 2018

1 reference

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

21 January 2018

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Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony

21 January 2018

1 reference

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

21 January 2018

1 reference

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

21 January 2018

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Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells

21 January 2018

1 reference

Autophagy is a critical mechanism for the induction of the antileukemic effects of arsenic trioxide

21 January 2018

1 reference

Methods in mammalian autophagy research

21 January 2018

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Purification of autophagosomes from rat hepatocytes.

21 January 2018

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The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes

21 January 2018

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

21 January 2018

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TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer

21 January 2018

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Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells.

21 January 2018

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Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma

21 January 2018

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Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.26374

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12 September 2017

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