(Q39190247)

9 September 2017

title

Gene methylation and silencing of SOCS3 in mantle cell lymphoma (English)

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9 September 2017

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Ommoleila Molavi

1

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9 September 2017

Peng Wang

2

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9 September 2017

Zoulika Zak

3

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9 September 2017

Pascal Gelebart

4

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9 September 2017

Andrew Belch

5

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9 September 2017

Raymond Lai

6

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9 September 2017

language of work or name

English

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publication date

22 February 2013

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British Journal of Haematology

9 September 2017

published in

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9 September 2017

volume

161

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9 September 2017

issue

3

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9 September 2017

page(s)

348-356

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STAT3 as a target for inducing apoptosis in solid and hematological tumors

9 September 2017

cites work

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Effect of 5-azacytidine on gene expression in marrow stromal cells

21 January 2018

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Constitutive and B-cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma

21 January 2018

1 reference

Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells

21 January 2018

1 reference

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

21 January 2018

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Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mechanism

21 January 2018

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Therapeutic options in mantle cell lymphoma

21 January 2018

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Concurrent disruption of cell cycle associated genes in mantle cell lymphoma: a genotypic and phenotypic study of cyclin D1, p16, p15, p53 and pRb.

21 January 2018

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SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer

21 January 2018

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 January 2018

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Epigenetic alterations in cholangiocarcinoma-sustained IL-6/STAT3 signaling in cholangio- carcinoma due to SOCS3 epigenetic silencing

21 January 2018

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Overexpression of SOCS3 exhibits preclinical antitumor activity against malignant pleural mesothelioma

21 January 2018

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Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics

21 January 2018

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Are SOCS suppressors, regulators, and degraders?

21 January 2018

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Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways

21 January 2018

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Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway

21 January 2018

1 reference

SOCS proteins: negative regulators of cytokine signaling

21 January 2018

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Suppressors of cytokine signaling and immunity

21 January 2018

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Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours

21 January 2018

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Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas

21 January 2018

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Pharmacological approach for optimization of the dose schedule of 5-Aza-2'-deoxycytidine (Decitabine) for the therapy of leukemia

21 January 2018

1 reference

Molecular biology of mantle cell lymphoma: from profiling studies to new therapeutic strategies

21 January 2018

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Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis.

21 January 2018

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Regulatory Effect of SOCS on NF-κB Activity in Murine Monocytes/Macrophages

21 January 2018

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Pim-1 kinase inhibits STAT5-dependent transcription via its interactions with SOCS1 and SOCS3.

21 January 2018

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Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis

21 January 2018

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Mantle cell lymphomas lack expression of p27Kip1, a cyclin-dependent kinase inhibitor

21 January 2018

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Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon

21 January 2018

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Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma

21 January 2018

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Altered apoptosis pathways in mantle cell lymphoma

21 January 2018

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Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

21 January 2018

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Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma

21 January 2018

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Mantle cell lymphoma: advances in biology and therapy

21 January 2018

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Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma

21 January 2018

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A family of cytokine-inducible inhibitors of signalling

21 January 2018

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Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

21 January 2018

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Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.

21 January 2018

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Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line

21 January 2018

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JAK/STAT signal transduction: regulators and implication in hematological malignancies

21 January 2018

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Methylation-associated dysregulation of the suppressor of cytokine signaling-3 gene in multiple myeloma

21 January 2018

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STATs in cancer inflammation and immunity: a leading role for STAT3

21 January 2018

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Restoration of SOCS3 suppresses human lung adenocarcinoma cell growth by downregulating activation of Erk1/2, Akt apart from STAT3.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/BJH.12262

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9 September 2017

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