(Q39207550)

10 September 2017

title

A CHO cell line engineered to express XBP1 and ERO1-Lα has increased levels of transient protein expression (English)

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10 September 2017

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Katharine Cain

1

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10 September 2017

Shirley Peters

2

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10 September 2017

Hanna Hailu

3

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10 September 2017

Bernie Sweeney

4

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Paul Stephens

5

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James Heads

6

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Kaushik Sarkar

7

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10 September 2017

Andy Ventom

8

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10 September 2017

Catherine Page

9

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10 September 2017

Alan Dickson

10

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10 September 2017

publication date

20 March 2013

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10 September 2017

published in

Biotechnology Progress

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10 September 2017

volume

29

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10 September 2017

issue

3

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10 September 2017

page(s)

697-706

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describes a project that uses

10 September 2017

CHOS-XE

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cites work

Coexpression of acidic fibroblast growth factor enhances specific productivity and antibody titers in transiently transfected HEK293 cells

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A simple high-yielding process for transient gene expression in CHO cells.

21 January 2018

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Production of recombinant protein therapeutics in cultivated mammalian cells

21 January 2018

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Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives

21 January 2018

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Large-scale transfection of mammalian cells for the fast production of recombinant protein

21 January 2018

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Mild hypothermia improves transient gene expression yields several fold in Chinese hamster ovary cells

21 January 2018

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Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells

21 January 2018

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Manufacturing recombinant proteins in kg-ton quantities using animal cells in bioreactors

21 January 2018

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Identifying bottlenecks in transient and stable production of recombinant monoclonal-antibody sequence variants in Chinese hamster ovary cells

21 January 2018

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Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line

21 January 2018

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Effect of inducible co-overexpression of protein disulfide isomerase and endoplasmic reticulum oxidoreductase on the specific antibody productivity of recombinant Chinese hamster ovary cells

21 January 2018

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Xbp1-based engineering of secretory capacity enhances the productivity of Chinese hamster ovary cells.

21 January 2018

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An XBP-1 dependent bottle-neck in production of IgG subtype antibodies in chemically defined serum-free Chinese hamster ovary (CHO) fed-batch processes

21 January 2018

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Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L).

21 January 2018

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Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells

21 January 2018

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

21 January 2018

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Effects of overexpression of X-box binding protein 1 on recombinant protein production in Chinese hamster ovary and NS0 myeloma cells

21 January 2018

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Disulfide transfer between two conserved cysteine pairs imparts selectivity to protein oxidation by Ero1

21 January 2018

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ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum

21 January 2018

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The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1‐Lα

21 January 2018

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Endoplasmic reticulum oxidoreductin 1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response

21 January 2018

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Manipulation of oxidative protein folding and PDI redox state in mammalian cells

21 January 2018

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Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

21 January 2018

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Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

21 January 2018

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Evaluation of a combinatorial cell engineering approach to overcome apoptotic effects in XBP-1(s) expressing cells

21 January 2018

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Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

21 January 2018

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Control of culture environment for improved polyethylenimine-mediated transient production of recombinant monoclonal antibodies by CHO cells.

21 January 2018

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Optimization of transient gene expression in mammalian cells and potential for scale-up using flow electroporation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BTPR.1693

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release_qdgwyaji5re2ji6afghrk546mq

10 September 2017

Fatcat ID

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